About   Help   FAQ
Sprr2a3 Gene Detail
Summary
  • Symbol
    Sprr2a3
  • Name
    small proline-rich protein 2A3
  • Feature Type
    protein coding gene
  • IDs
    MGI:3845028
    NCBI Gene: 100042514
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:92192611-92196571 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 40.14 cM
Strain
Comparison
more
  • SNPs within 2kb
    51 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3845028
 protein coding gene Chr3:92192611-92198712 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0027453
 protein coding gene Chr3:89763319-89766482 (+)
AKR/J MGP_AKRJ_G0027418
 protein coding gene Chr3:91944049-91947723 (+)
BALB/cJ MGP_BALBcJ_G0027463
 protein coding gene Chr3:89599266-89618885 (+)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0027305
 protein coding gene Chr3:105793830-105798387 (+)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0026383
 protein coding gene Chr3:88996182-89001627 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026203
 protein coding gene Chr3:89958964-89959644 (+)
WSB/EiJ MGP_WSBEiJ_G0026731
 protein coding gene Chr3:91924554-91929389 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    2
  • cDNA Data
    41
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100042514 NCBI Gene Model | MGI Sequence Detail 3961 C57BL/6J ±  kb
transcript NM_001309382 RefSeq | MGI Sequence Detail 852 C57BL/6  
polypeptide Q4KL71 UniProt | EBI | MGI Sequence Detail 83 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:52302 Song HJ, et al., Mouse Sprr2 genes: a clustered family of genes showing differential expression in epithelial tissues. Genomics. 1999 Jan 1;55(1):28-42
  • Latest
    J:314159 Hu Z, et al., Small proline-rich protein 2A is a gut bactericidal protein deployed during helminth infection. Science. 2021 Nov 5;374(6568):eabe6723
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory