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Methig1 Gene Detail
Summary
  • Symbol
    Methig1
  • Name
    methyltransferase hypoxia inducible domain containing 1
  • Synonyms
    AB099516, Mettl7a2-Higd1c, Mettl7a2Higd1c, UbiE2-Hig1-4, UbiE-YGHL1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3845761
    NCBI Gene: 554292
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr15:100251081-100282316 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.27 cM
Strain
Comparison
more
  • SNPs within 2kb
    1077 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3845761
 protein coding gene Chr15:100251030-100282317 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0022311
 protein coding gene Chr15:98217404-98307979 (+)
AKR/J MGP_AKRJ_G0022287
 protein coding gene Chr15:101281686-101311641 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022083
 protein coding gene Chr15:101295272-101391557 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022762
 protein coding gene Chr15:106129528-106180738 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020285
 protein coding gene Chr15:94046998-94048054 (+)
CAST/EiJ MGP_CASTEiJ_G0021607
 protein coding gene Chr15:102136892-102249207 (+)
CBA/J MGP_CBAJ_G0022051
 protein coding gene Chr15:109766101-109827842 (+)
DBA/2J MGP_DBA2J_G0022181
 protein coding gene Chr15:97644034-97675787 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0022249
 protein coding gene Chr15:102380918-102516434 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022178
 protein coding gene Chr15:113517177-113552415 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022774
 protein coding gene Chr15:101285355-101319703 (+)
PWK/PhJ MGP_PWKPhJ_G0021347
 protein coding gene Chr15:97769985-97801511 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021181
 protein coding gene Chr15:101142878-101214021 (+)
WSB/EiJ MGP_WSBEiJ_G0021657
 protein coding gene Chr15:101819496-101946849 (+)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Methig1
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 554292 NCBI Gene Model | MGI Sequence Detail 31236 C57BL/6J ±  kb
transcript NM_001024672 RefSeq | MGI Sequence Detail 1449 C57BL/6  
polypeptide NP_001019843 RefSeq | MGI Sequence Detail 264 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR007667 Hypoxia induced protein, domain
    IPR013216 Methyltransferase type 11
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    IPR052356 Thiol S-methyltransferase
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 32
    Diseases 1
    Phenotypes 20
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory