Ighv3-1 Gene Detail

Summary

• Symbol
  Ighv3-1
• Name
  immunoglobulin heavy variable 3-1
• Synonyms
  Gm16610

• Feature Type
  gene segment
• IDs
  MGI:4439534
  NCBI Gene: 780803
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr12:113928010-113928303 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 62.24 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  65 from dbSNP Build 142
• Strain Annotations
  14

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439534	gene segment	Chr12:113928008-113928438 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0000054	gene segment	Chr12:116555698-116556127 (-)
A/J	MGP_AJ_G0000054	gene segment	Chr12:112097732-112098161 (-)
AKR/J	MGP_AKRJ_G0000056	gene segment	Chr12:115463938-115464368 (-)
BALB/cJ	MGP_BALBcJ_G0000052	gene segment	Chr12:112506598-112507027 (-)
C3H/HeJ	MGP_C3HHeJ_G0000053	gene segment	Chr12:115884327-115884757 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0000076	gene segment	Chr12:120269564-120269994 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0000051	gene segment	Chr12:124801981-124802411 (-)
DBA/2J	MGP_DBA2J_G0000055	gene segment	Chr12:111670255-111670684 (-)
FVB/NJ	MGP_FVBNJ_G0000055	gene segment	Chr12:110447411-110447799 (-)
LP/J	MGP_LPJ_G0000060	gene segment	Chr12:116500608-116501038 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0000058	gene segment	Chr12:127939848-127940277 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0000068	gene segment	Chr12:114867158-114867588 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0000058	gene segment	Chr12:115802744-115803173 (-)

Homology

• Human Ortholog
  IGHV4-28, immunoglobulin heavy variable 4-28

• Vertebrate Orthologs
  17

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGHV4-28, immunoglobulin heavy variable 4-28
  
• Synonyms
  IGHV428, VH
• Links
  HGNC:5645

  NCBI Gene ID: 28400

  UniProt: A0A0C4DH34

  
  
• Chr Location
  14q32.33; chr14:106324254-106324760 (-)  GRCh38

---

• Human Ortholog
  IGHV4-30-2, immunoglobulin heavy variable 4-30-2
  
• Synonyms
  IGHV4-3, IGHV4302
• Links
  HGNC:5647

  NCBI Gene ID: 28398

  
  
• Chr Location
  14q32.33; chr14:106349283-106349720 (-)  GRCh38

---

• Human Ortholog
  IGHV4-31, immunoglobulin heavy variable 4-31
  
• Synonyms
  IGHV431
• Links
  HGNC:5649

  NCBI Gene ID: 28396

  UniProt: P0DP07

  
  
• Chr Location
  14q32.33; chr14:106349283-106349792 (-)  GRCh38

---

• Human Ortholog
  IGHV4-34, immunoglobulin heavy variable 4-34
  
• Synonyms
  IGHV434, VH
• Links
  HGNC:5650

  NCBI Gene ID: 28395

  UniProt: P06331

  
  
• Chr Location
  14q32.33; chr14:106373661-106374145 (-)  GRCh38

---

• Human Ortholog
  IGHV4-38-2, immunoglobulin heavy variable 4-38-2
  
• Synonyms
  IGHV4-B, IGHV4B
• Links
  HGNC:5657

  NCBI Gene ID: 28389

  UniProt: P0DP08

  
  
• Chr Location
  14q32.33

---

• Human Ortholog
  IGHV4-39, immunoglobulin heavy variable 4-39
  
• Synonyms
  IGHV439, VH
• Links
  HGNC:5651

  NCBI Gene ID: 28394

  UniProt: P01824

  
  
• Chr Location
  14q32.33; chr14:106421709-106422218 (-)  GRCh38

---

• Human Ortholog
  IGHV4-4, immunoglobulin heavy variable 4-4
  
• Synonyms
  IGHV44, VH
• Links
  HGNC:5652

  NCBI Gene ID: 28401

  UniProt: A0A075B6R2

  
  
• Chr Location
  14q32.33; chr14:106011922-106012420 (-)  GRCh38

---

• Human Ortholog
  IGHV4-59, immunoglobulin heavy variable 4-59
  
• Synonyms
  IGHV459, VH
• Links
  HGNC:5654

  NCBI Gene ID: 28392

  UniProt: P01825

  
  
• Chr Location
  14q32.33; chr14:106627249-106627825 (-)  GRCh38

---

• Human Ortholog
  IGHV4-61, immunoglobulin heavy variable 4-61
  
• Synonyms
  IGHV461, VH
• Links
  HGNC:5655

  NCBI Gene ID: 28391

  UniProt: A0A0C4DH41

  
  
• Chr Location
  14q32.33; chr14:106639119-106639657 (-)  GRCh38

---

• Human Ortholog
  IGHV4OR15-8, immunoglobulin heavy variable 4/OR15-8 (non-functional)
  
• Synonyms
  IGHV4OR158, VSIG6
• Links
  HGNC:5658

  NCBI Gene ID: 28317

  
  
• Chr Location
  15q11.2; chr15:22184967-22185402 (-)  GRCh38

---

• Human Ortholog
  IGHV6-1, immunoglobulin heavy variable 6-1
  
• Synonyms
  IGHV61, VH
• Links
  HGNC:5662

  NCBI Gene ID: 28385

  UniProt: A0A0B4J1U7

  
  
• Chr Location
  14q32.33; chr14:105939754-105940253 (-)  GRCh38

---

• MGI Vertebrate Homology
  Ighv3-1 stringent orthology
  11 human;1 mouse;1 rat;5 zebrafish
  
• HCOP
  vertebrate homology predictions: IGHV4-28, IGHV4-30-2, IGHV4-31, IGHV4-34, IGHV4-38-2, IGHV4-39, IGHV4-4, IGHV4-59, IGHV4-61, IGHV4OR15-8, IGHV6-1
• Gene Tree
  Ighv3-1
  

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  1

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  20
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000093838 (Evidence)
• NCBI Gene
  780803

Representative Sequences			Length	Strain/Species
genomic	780803	NCBI Gene Model | MGI Sequence Detail	294	C57BL/6J
polypeptide	A0A075B5S6	UniProt | EBI | MGI Sequence Detail	116	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR050199 Immunoglobulin Heavy Variable
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain

References

• Summaries
  All 6

  Gene Ontology 1
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Ighv3-1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr118055	Chr12:113928485-113928494 (-)	-187 bp