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Ighv14-2 Gene Detail
Summary
  • Symbol
    Ighv14-2
  • Name
    immunoglobulin heavy variable 14-2
  • Synonyms
    Gm16683
  • Feature Type
    gene segment
  • IDs
    MGI:4439607
    NCBI Gene: 668421
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113958089-113958518 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    84 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439607
 gene segment Chr12:113958089-113958518 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0000060
 gene segment Chr12:115553605-115554034 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0000057
 gene segment Chr12:115916562-115916991 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000074
 gene segment Chr12:120190496-120190925 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0000054
 gene segment Chr12:124832350-124832779 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0000061
 gene segment Chr12:116538480-116538909 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0000071
 gene segment Chr12:114894452-114894881 (-)
PWK/PhJ MGP_PWKPhJ_G0000049
 gene segment Chr12:106310615-106412900 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38
  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1-F, IGHV1F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
  • All Sequences
    16
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 668421 NCBI Gene Model | MGI Sequence Detail 430 C57BL/6J ±  kb
transcript AK134885 GenBank | ENA | DDBJ | MGI Sequence Detail 2486 C57BL/6J  
polypeptide A0A075B5R7 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1
References
more
  • Summaries
    All 7
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory