Ighv1-37 Gene Detail

Summary

• Symbol
  Ighv1-37
• Name
  immunoglobulin heavy variable 1-37
• Synonyms
  Gm16716

• Feature Type
  gene segment
• IDs
  MGI:4439640
  NCBI Gene: 668517
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr12:114859858-114860151 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 62.46 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  200 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439640	gene segment	Chr12:114859858-114860291 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  IGHV1-45, immunoglobulin heavy variable 1-45

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IGHV1-45, immunoglobulin heavy variable 1-45
  
• Synonyms
  IGHV145, VH
• Links
  HGNC:5553

  NCBI Gene ID: 28466

  UniProt: A0A0A0MS14

  
  
• Chr Location
  14q32.33; chr14:106506996-106507491 (-)  GRCh38

---

• MGI Vertebrate Homology
  Ighv1-37 stringent orthology
  1 human;1 mouse;3 zebrafish
  
• HCOP
  vertebrate homology predictions: IGHV1-45
• Gene Tree
  Ighv1-37
  

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  7
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000095923 (Evidence)
• NCBI Gene
  668517

Representative Sequences			Length	Strain/Species
genomic	668517	NCBI Gene Model | MGI Sequence Detail	294	C57BL/6J
polypeptide	A0A0A6YW32	UniProt | EBI | MGI Sequence Detail	117	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR050199 Immunoglobulin Heavy Variable
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain

References

• Summaries
  All 5
• Earliest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Ighv1-37:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr3977	Chr12:114860341-114860345 (-)	-192 bp