About   Help   FAQ
Ighv1-78 Gene Detail
Summary
  • Symbol
    Ighv1-78
  • Name
    immunoglobulin heavy variable 1-78
  • Synonyms
    Gm16812
  • Feature Type
    gene segment
  • IDs
    MGI:4439736
    NCBI Gene: 213570
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:115832393-115832686 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 62.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    353 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_4439736
 gene segment Chr12:115832393-115832847 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0000094
 gene segment Chr12:114351493-114351777 (-)
AKR/J MGP_AKRJ_G0000090
 gene segment Chr12:117783544-117783998 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0000091
 gene segment Chr12:118117974-118118428 (-)
C57BL/6NJ MGP_C57BL6NJ_G0000138
 gene segment Chr12:122450361-122450815 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0000095
 gene segment Chr12:112030941-112031395 (-)
CBA/J MGP_CBAJ_G0000090
 gene segment Chr12:127329707-127330161 (-)
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0000101
 gene segment Chr12:118874473-118874930 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0000105
 gene segment Chr12:130605022-130605476 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0000119
 gene segment Chr12:117045036-117045490 (-)
PWK/PhJ MGP_PWKPhJ_G0000081
 gene segment Chr12:108583346-108583913 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0000093
 gene segment Chr12:118083422-118083880 (-)



Homology
more
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGHV1-24, immunoglobulin heavy variable 1-24
  • Synonyms
    IGHV124, VH
  • Links
    NCBI Gene ID: 28467
    UniProt: A0A0C4DH33

  • Chr Location
    14q32.33; chr14:106276546-106277043 (-)  GRCh38
  • Human Ortholog
    IGHV1-45, immunoglobulin heavy variable 1-45
  • Synonyms
    IGHV145, VH
  • Links
    NCBI Gene ID: 28466
    UniProt: A0A0A0MS14

  • Chr Location
    14q32.33; chr14:106506996-106507491 (-)  GRCh38
  • Human Ortholog
    IGHV1-69-2, immunoglobulin heavy variable 1-69-2
  • Synonyms
    IGHV1-F, IGHV1F
  • Links
    NCBI Gene ID: 28458
    UniProt: A0A0G2JMI3

  • Chr Location
    14q32.33; chr14:106737110-106737547 (-)  GRCh38
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    21
  • RefSeq
    1
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 213570 NCBI Gene Model | MGI Sequence Detail 294 C57BL/6J ±  kb
polypeptide A0A0G2JGN3 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050199 Immunoglobulin Heavy Variable
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
References
more
  • Summaries
    All 6
    Gene Ontology 1
  • Earliest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory