Carmn MGI Mouse Gene Detail - MGI:4439832 - cardiac mesoderm enhancer-associated non-coding RNA

Symbol

Carmn
Name

cardiac mesoderm enhancer-associated non-coding RNA
Synonyms

Carmen, Mir143hg

Feature Type

lncRNA gene
IDs

MGI:4439832
NCBI Gene: 328968
Alliance

gene page
Transcription Start Sites

16 TSS

Sequence Map

Chr18:61782696-61798608 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 18, 34.64 cM
Mapping Data

1 experiment

SNPs within 2kb

491 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4439832	lncRNA gene	Chr18:61778947-61798608 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0005794	lincRNA gene	Chr18:61549177-61565585 (-)
A/J	MGP_AJ_G0005783	lincRNA gene	Chr18:58906702-58922618 (-)
AKR/J	MGP_AKRJ_G0005760	lincRNA gene	Chr18:60528391-60544305 (-)
BALB/cJ	MGP_BALBcJ_G0005762	lincRNA gene	Chr18:59030726-59046654 (-)
C3H/HeJ	MGP_C3HHeJ_G0005710	lincRNA gene	Chr18:60761406-60777286 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0005923	lincRNA gene	Chr18:63220917-63236828 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0005266	lincRNA gene	Chr18:58452446-58468494 (-)
CAST/EiJ	MGP_CASTEiJ_G0005651	lincRNA gene	Chr18:60642491-60659053 (-)
CBA/J	MGP_CBAJ_G0005697	lincRNA gene	Chr18:65269367-65288387 (-)
DBA/2J	MGP_DBA2J_G0005715	lincRNA gene	Chr18:58576053-58592163 (-)
FVB/NJ	MGP_FVBNJ_G0005742	lincRNA gene	Chr18:57982138-57999327 (-)
LP/J	MGP_LPJ_G0005796	lincRNA gene	Chr18:61406479-61422403 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0005728	lincRNA gene	Chr18:66837606-66854791 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0005921	lincRNA gene	Chr18:60734705-60752842 (-)
PWK/PhJ	MGP_PWKPhJ_G0005596	lincRNA gene	Chr18:58806726-58822740 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0005512	lincRNA gene	Chr18:60962706-60979137 (-)
WSB/EiJ	MGP_WSBEiJ_G0005703	lincRNA gene	Chr18:60588702-60605045 (-)

Human Ortholog

CARMN, cardiac mesoderm enhancer-associated non-coding RNA

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CARMN, cardiac mesoderm enhancer-associated non-coding RNA
Synonyms

CARMEN, MIR143HG
Links

HGNC:42872

NCBI Gene ID: 728264
Chr Location

5q32; chr5:149406689-149432836 (+) GRCh38

MGI Vertebrate Homology

Carmn stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: CARMN
Gene Tree

Carmn

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Phenotype Summary

5 phenotype references

All Mutations and Alleles

3
Endonuclease-mediated

1
Gene trapped

1
Targeted

1
Find Mice (IMSR)

2 strains or lines available

Mice homozygous for a conditional allele activated in vascular smooth muscle exhibit exacerbated neointima formation and increased vascular smooth muscle cell proliferation following left carotid artery ligation.

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All GO Annotations

2
GO References

1

Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

812
Tissues

67
cDNA Data

3
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

32
RefSeq

1

Ensembl

ENSMUSG00000097324 (Evidence)
NCBI Gene

328968

Representative Sequences				Length	Strain/Species	Flank
	genomic	ENSMUSG00000097324	Ensembl Gene Model \| MGI Sequence Detail	15913	C57BL/6J	± kb
	transcript	ENSMUST00000241376	Ensembl \| MGI Sequence Detail	2596	Not Applicable

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All nucleic 12

cDNA 3

Primer pair 8

Other 1

Summaries

All 14

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 5
Earliest

J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
Latest

J:338926 He X, et al., The Long Noncoding RNA Cardiac Mesoderm Enhancer-Associated Noncoding RNA (Carmn) Is a Critical Regulator of Gastrointestinal Smooth Muscle Contractile Function and Motility. Gastroenterology. 2023 Apr 6;

TSS for Carmn:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr153601	Chr18:61798596-61798603 (-)	8 bp
Tssr153600	Chr18:61798555-61798573 (-)	44 bp
Tssr153599	Chr18:61798472-61798487 (-)	128 bp
Tssr153598	Chr18:61791383-61791404 (-)	7,214 bp
Tssr153597	Chr18:61791337-61791351 (-)	7,264 bp
Tssr153596	Chr18:61791240-61791255 (-)	7,360 bp
Tssr153595	Chr18:61791211-61791227 (-)	7,389 bp
Tssr153594	Chr18:61791119-61791206 (-)	7,445 bp
Tssr153593	Chr18:61791085-61791100 (-)	7,515 bp
Tssr153592	Chr18:61791048-61791078 (-)	7,545 bp
Tssr153591	Chr18:61791027-61791043 (-)	7,573 bp
Tssr153590	Chr18:61790952-61790998 (-)	7,633 bp
Tssr153589	Chr18:61785520-61785535 (-)	13,080 bp
Tssr153588	Chr18:61785490-61785511 (-)	13,107 bp
Tssr153587	Chr18:61785457-61785468 (-)	13,145 bp
Tssr153586	Chr18:61785428-61785444 (-)	13,172 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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