Trav12-1 Gene Detail

Summary

• Symbol
  Trav12-1
• Name
  T cell receptor alpha variable 12-1
• Synonyms
  Gm17011

• Feature Type
  gene segment
• IDs
  MGI:4440525
  NCBI Gene: 630086
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr14:53775723-53776195 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 14, 27.41 cM

Strain
Comparison

• SNPs within 2kb
  182 from dbSNP Build 142
• Strain Annotations
  6

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4440525	gene segment	Chr14:53775648-53776195 (+)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0002520	gene segment	Chr14:46016646-46017204 (+)
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0002451	gene segment	Chr14:44149317-44149864 (+)
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0002476	gene segment	Chr14:45432788-45433332 (+)
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0002665	gene segment	Chr14:47395843-47396390 (+)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0002485	gene segment	Chr14:47329736-47330293 (+)

Homology

• Human Ortholog
  TRAV18, T cell receptor alpha variable 18

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  TRAV18, T cell receptor alpha variable 18
  
• Synonyms
  TCRAV18S1
• Links
  HGNC:12114

  NCBI Gene ID: 28665

  UniProt: A0A075B6X5

  
  
• Chr Location
  14q11.2; chr14:22003106-22003673 (+)  GRCh38

---

• MGI Vertebrate Homology
  Trav12-1 stringent orthology
  1 human;1 mouse;2 zebrafish
  
• HCOP
  vertebrate homology predictions: TRAV18
• Gene Tree
  Trav12-1
  

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  13
• RefSeq
  1
• UniProt
  1

• Ensembl
  ENSMUSG00000096825 (Evidence)
• NCBI Gene
  630086

Representative Sequences			Length	Strain/Species
genomic	630086	NCBI Gene Model | MGI Sequence Detail	473	C57BL/6J
transcript	BC038136	GenBank | ENA | DDBJ | MGI Sequence Detail	768	C57BL/6
polypeptide	A0N8R1	UniProt | EBI | MGI Sequence Detail	115	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• InterPro Domains
  IPR007110 Immunoglobulin-like domain
  IPR036179 Immunoglobulin-like domain superfamily
  IPR013783 Immunoglobulin-like fold
  IPR013106 Immunoglobulin V-set domain
  IPR051287 T cell receptor variable region

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 7
• Earliest
  J:23982 Chou HS, et al., T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments. EMBO J. 1986 Sep;5(9):2149-55
• Latest
  J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

TSS for Trav12-1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr125482	Chr14:53775703-53775715 (+)	-14 bp