Dp(17Abcg1-Rrp1b)3Yey Cytogenetic Marker Detail

Summary

• Symbol
  Dp(17Abcg1-Rrp1b)3Yey
• Name
  duplication, Chr 17, Y Eugene Yu 3
• Synonyms
  Dp(17)1Yey, Dp(17Abcg1-Rrp1b)1Yey, Ts3Yey

• Feature Type
  chromosomal duplication
• IDs
  MGI:4461398

Location &
Maps

• Sequence Map
  Chr17:31276672-32281839 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, Syntenic

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  16 phenotypes from multigenic genotypes
  20 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  3 strains or lines available

References

• Summaries
  All 21

  Diseases 1

  Phenotypes 20
• Earliest
  J:161325 Yu T, et al., A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions. Hum Mol Genet. 2010 Jul 15;19(14):2780-91
• Latest
  J:357279 Donovan MG, et al., Multimodal analysis of dysregulated heme metabolism, hypoxic signaling, and stress erythropoiesis in Down syndrome. Cell Rep. 2024 Aug 27;43(8):114599