Pate1 Gene Detail

Summary

• Symbol
  Pate1
• Name
  prostate and testis expressed 1
• Synonyms
  Gm17252

• Feature Type
  protein coding gene
• IDs
  MGI:4936886
  NCBI Gene: 100312987
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr9:35596375-35598686 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 20.39 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  121 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_4936886	protein coding gene	Chr9:35596182-35598686 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034542	protein coding gene	Chr9:33498276-33500586 (-)
A/J	MGP_AJ_G0034520	protein coding gene	Chr9:32643901-32646211 (-)
AKR/J	MGP_AKRJ_G0034446	protein coding gene	Chr9:33364484-33366796 (-)
BALB/cJ	MGP_BALBcJ_G0034511	protein coding gene	Chr9:32546493-32548803 (-)
C3H/HeJ	MGP_C3HHeJ_G0034223	protein coding gene	Chr9:33700713-33703023 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0035032	protein coding gene	Chr9:34626973-34629284 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031962	protein coding gene	Chr9:31308018-31310325 (-)
CAST/EiJ	MGP_CASTEiJ_G0033546	protein coding gene	Chr9:33605518-33607825 (-)
CBA/J	MGP_CBAJ_G0034197	protein coding gene	Chr9:35779510-35781831 (-)
DBA/2J	MGP_DBA2J_G0034354	protein coding gene	Chr9:32614503-32616814 (-)
FVB/NJ	MGP_FVBNJ_G0034297	protein coding gene	Chr9:32035065-32037375 (-)
LP/J	MGP_LPJ_G0034440	protein coding gene	Chr9:33747126-33749438 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034341	protein coding gene	Chr9:37360176-37362487 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035052	protein coding gene	Chr9:33321345-33323657 (-)
PWK/PhJ	MGP_PWKPhJ_G0033251	protein coding gene	Chr9:32597059-32599366 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0033086	protein coding gene	Chr9:33596198-33598520 (-)
WSB/EiJ	MGP_WSBEiJ_G0033661	protein coding gene	Chr9:33099481-33101783 (-)

Homology

• Human Ortholog
  PATE1, prostate and testis expressed 1

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PATE1, prostate and testis expressed 1
  
• Synonyms
  PATE
• Links
  HGNC:24664

  NCBI Gene ID: 160065

  neXtProt AC: NX_Q8WXA2

  UniProt: Q8WXA2

  
  
• Chr Location
  11q24.2; chr11:125746279-125749867 (+)  GRCh38

---

• MGI Vertebrate Homology
  Pate1 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: PATE1
• Gene Tree
  Pate1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  2
• Endonuclease-mediated
  2
• Genomic Mutations
  1 involving Pate1
• Find Mice (IMSR)
  11 strains or lines available

Male mice exhibit normal spermatozoa and fecundity.

Expression

• Assay Results
  706
• cDNA Data
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  27
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS57669.1

• Ensembl
  ENSMUSG00000091215 (Evidence)
• NCBI Gene
  100312987

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000091215	Ensembl Gene Model | MGI Sequence Detail	2312	C57BL/6J
transcript	ENSMUST00000170021	Ensembl | MGI Sequence Detail	389	Not Applicable
polypeptide	ENSMUSP00000130484	Ensembl | MGI Sequence Detail	125	Not Applicable

Protein
Information

• UniProt
  1 Sequence

Molecular
Reagents

• All nucleic 1

  cDNA 1

References

• Summaries
  All 11

  Phenotypes 2
• Earliest
  J:138601 Levitin F, et al., PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity. J Biol Chem. 2008 Jun 13;283(24):16928-39
• Latest
  J:279308 Fujihara Y, et al., Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18498-18506

TSS for Pate1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr88761	Chr9:35598682-35598687 (-)	1 bp
Tssr88760	Chr9:35598310-35598329 (-)	366 bp