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Tle7 Gene Detail
Summary
  • Symbol
    Tle7
  • Name
    TLE family member 7
  • Synonyms
    Gm21964
  • Feature Type
    protein coding gene
  • IDs
    MGI:5439433
    NCBI Gene: 102638837
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:110827964-110838646 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    329 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5439433
 protein coding gene Chr8:110827839-110838646 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034121
 protein coding gene Chr8:112746401-112748391 (+)
A/J MGP_AJ_G0034100
 protein coding gene Chr8:108176407-108178397 (+)
AKR/J MGP_AKRJ_G0034027
 protein coding gene Chr8:111358499-111360489 (+)
BALB/cJ MGP_BALBcJ_G0034094
 protein coding gene Chr8:108377824-108379814 (+)
C3H/HeJ MGP_C3HHeJ_G0033805
 protein coding gene Chr8:112057899-112059889 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034614
 protein coding gene Chr8:116725521-116727511 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031556
 protein coding gene Chr8:101202854-101204840 (+)
CAST/EiJ MGP_CASTEiJ_G0033132
 protein coding gene Chr8:111663661-111665651 (+)
CBA/J MGP_CBAJ_G0033779
 protein coding gene Chr8:120649694-120651684 (+)
DBA/2J MGP_DBA2J_G0033934
 protein coding gene Chr8:107497380-107499370 (+)
FVB/NJ MGP_FVBNJ_G0033878
 protein coding gene Chr8:106443122-106445112 (+)
LP/J MGP_LPJ_G0034024
 protein coding gene Chr8:112925465-112927455 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033924
 protein coding gene Chr8:123642913-123644903 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034633
 protein coding gene Chr8:111308851-111310841 (+)
PWK/PhJ MGP_PWKPhJ_G0032835
 protein coding gene Chr8:107062107-107064097 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032674
 protein coding gene Chr8:109998117-110000108 (+)
WSB/EiJ MGP_WSBEiJ_G0033248
 protein coding gene Chr8:111995203-111997193 (+)



Homology
more
  • Human Ortholog
    TLE7, TLE family member 7
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TLE7, TLE family member 7
  • Synonyms
    chico
  • Links
    NCBI Gene ID: 102723796
    UniProt: A0A1W2PR48

  • Chr Location
    chr16:71429980-71442054 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 102638837 NCBI Gene Model | MGI Sequence Detail 10683 C57BL/6J ±  kb
transcript NM_001370839 RefSeq | MGI Sequence Detail 1577 ZRU/MplStud  
polypeptide NP_001357768 RefSeq | MGI Sequence Detail 430 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009146 Groucho/transducin-like enhancer
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Other
Accession IDs
less
MGI:6280698
References
more
  • Summaries
    All 8
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:293217 GemPharmatech, GemPharmatech Website. 2020;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory