About   Help   FAQ
Igs2 Other Genome Feature Detail
Summary
  • Symbol
    Igs2
  • Name
    intergenic site 2
  • Synonyms
    H11, Hipp11, Iis2
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:5461148
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Personal communications (Evgeny Kvon) and J:352731: GRCm39: chr11:3195460-3195497 (GRCm38: chr11:3245460-3245497); insertion results in 38 bp deletion.
  • Genetic Map
    Chromosome 11, Syntenic
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 7 alleles in 4 genetic backgrounds
    19 phenotypes from multigenic genotypes
    207 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for knock-in alleles exhibit no abnormal phenotype.
References
more
  • Summaries
    All 209
    Diseases 2
    Phenotypes 207
  • Earliest
    J:166047 Hippenmeyer S, et al., Genetic mosaic dissection of lis1 and ndel1 in neuronal migration. Neuron. 2010 Nov 18;68(4):695-709
  • Latest
    J:355476 Hua X, et al., A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia. Elife. 2024 Sep 25;13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory