Lhx5as1 Gene Detail

Summary

• Symbol
  Lhx5as1
• Name
  LIM homeobox 5, antisense 1
• Synonyms
  Gm27199

• Feature Type
  lncRNA gene
• IDs
  MGI:5521042
  NCBI Gene: 102634302
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr5:120557721-120569832 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  348 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5521042	lncRNA gene	Chr5:120557719-120569832 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0004163	antisense lncRNA gene	Chr5:123773674-123785550 (-)
A/J	MGP_AJ_G0004142	antisense lncRNA gene	Chr5:118646681-118675760 (-)
AKR/J	MGP_AKRJ_G0004123	antisense lncRNA gene	Chr5:122485228-122501645 (-)
BALB/cJ	MGP_BALBcJ_G0004128	antisense lncRNA gene	Chr5:120075813-120091392 (-)
C3H/HeJ	MGP_C3HHeJ_G0004077	antisense lncRNA gene	Chr5:123021994-123035936 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0004277	antisense lncRNA gene	Chr5:128423472-128437612 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0003753	antisense lncRNA gene	Chr5:113371910-113383803 (-)
CAST/EiJ	MGP_CASTEiJ_G0004038	antisense lncRNA gene	Chr5:122131258-122150270 (-)
CBA/J	MGP_CBAJ_G0004071	antisense lncRNA gene	Chr5:133412144-133423668 (-)
DBA/2J	MGP_DBA2J_G0004086	antisense lncRNA gene	Chr5:118749078-118760444 (-)
FVB/NJ	MGP_FVBNJ_G0004102	antisense lncRNA gene	Chr5:117664552-117677294 (-)
LP/J	MGP_LPJ_G0004164	antisense lncRNA gene	Chr5:124232328-124252064 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0004092	antisense lncRNA gene	Chr5:137388619-137403334 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0004274	antisense lncRNA gene	Chr5:122061020-122074046 (-)
PWK/PhJ	MGP_PWKPhJ_G0003992	antisense lncRNA gene	Chr5:117505711-117518750 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0003935	antisense lncRNA gene	Chr5:119720419-119734965 (-)
WSB/EiJ	MGP_WSBEiJ_G0004075	antisense lncRNA gene	Chr5:122651139-122664878 (-)

Homology

• Gene Tree
  Lhx5as1
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 1 genetic background
  6 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Lhx5as1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele display decreased excitatory postsynaptic and miniature excitatory postsynaptic current amplitudes and impaired spatial learning and memory.

Expression

• Assay Results
  707
• Tissues
  1
• cDNA Data
  1
• Literature Summary
  3

Images

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  24
• RefSeq
  1

• Ensembl
  ENSMUSG00000098649 (Evidence)
• NCBI Gene
  102634302

Representative Sequences			Length	Strain/Species
genomic	102634302	NCBI Gene Model | MGI Sequence Detail	12112	C57BL/6J
transcript	NR_166585	RefSeq | MGI Sequence Detail	626	C57BL/6

Molecular
Reagents

• All nucleic 2

  cDNA 1

  Primer pair 1

Other
Accession IDs

MGI:5591135, MGI:7526333

References

• Summaries
  All 15

  Developmental Gene Expression 3

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:338207 Moreau MX, et al., Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons. Dev Cell. 2023 Jun 7;

TSS for Lhx5as1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr52923	Chr5:120569822-120569836 (-)	3 bp