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Tmem151a Gene Detail
Summary
  • Symbol
    Tmem151a
  • Name
    transmembrane protein 151A
  • Synonyms
    LOC381199, Tmem151
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147713
    NCBI Gene: 381199
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5120859-5135519 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, Syntenic
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    354 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147713
 protein coding gene Chr19:5120859-5135559 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024690
 protein coding gene Chr19:1998517-2012923 (-)
A/J MGP_AJ_G0024656
 protein coding gene Chr19:1895293-1909804 (-)
AKR/J MGP_AKRJ_G0024629
 protein coding gene Chr19:1944587-1959104 (-)
BALB/cJ MGP_BALBcJ_G0024656
 protein coding gene Chr19:1885797-1906134 (-)
C3H/HeJ MGP_C3HHeJ_G0024424
 protein coding gene Chr19:1947252-1962313 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025103
 protein coding gene Chr19:2055381-2069769 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022533
 protein coding gene Chr19:1824653-1840635 (-)
CAST/EiJ MGP_CASTEiJ_G0023896
 protein coding gene Chr19:1972700-1987227 (-)
CBA/J MGP_CBAJ_G0024395
 protein coding gene Chr19:2134838-2151685 (-)
DBA/2J MGP_DBA2J_G0024523
 protein coding gene Chr19:1880396-1894715 (-)
FVB/NJ MGP_FVBNJ_G0024490
 protein coding gene Chr19:1881021-1896539 (-)
LP/J MGP_LPJ_G0024609
 protein coding gene Chr19:1992803-2008791 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024520
 protein coding gene Chr19:2017695-2034255 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025151
 protein coding gene Chr19:1948047-1962582 (-)
PWK/PhJ MGP_PWKPhJ_G0023642
 protein coding gene Chr19:1917948-1932924 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023447
 protein coding gene Chr19:1935781-1951868 (-)
WSB/EiJ MGP_WSBEiJ_G0023958
 protein coding gene Chr19:1952117-1970156 (-)



Homology
more
  • Human Ortholog
    TMEM151A, transmembrane protein 151A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM151A, transmembrane protein 151A
  • Synonyms
    DYT36, EKD3, TMEM151
  • Links
    NCBI Gene ID: 256472
    neXtProt AC: NX_Q8N4L1
    UniProt: Q8N4L1

  • Chr Location
    11q13.2; chr11:66291894-66296664 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TMEM151A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Knock-out mice exhibit spontaneous dyskinesia attacks.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    34
  • cDNA Data
    15
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381199 NCBI Gene Model | MGI Sequence Detail 14661 C57BL/6J ±  kb
transcript NM_001001885 RefSeq | MGI Sequence Detail 3963 ZRU/MplStud  
polypeptide Q6GQT5 UniProt | EBI | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685807, MGI:5589786
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:330440 Li HF, et al., TMEM151A variants cause paroxysmal kinesigenic dyskinesia. Cell Discov. 2021 Sep 13;7(1):83
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory