Bxs7 QTL Detail

Summary

• Symbol
  Bxs7
• Name
  BXSB/MpJ autoimmune nephritis 7

• Feature Type
  QTL
• IDs
  MGI:5692198

Location &
Maps

• Sequence Map
  Chr13:45210442-83744746 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 13, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:145903 Haywood ME, et al., Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice. J Immunol. 2001 Aug 1;167(3):1728-33
• Latest
  J:145049 Rankin J, et al., The Bxs6 locus of BXSB mice is sufficient for high-level expression of gp70 and the production of gp70 immune complexes. J Immunol. 2007 Apr 1;178(7):4395-401