Gm45225 Pseudogene Detail

Summary

• Symbol
  Gm45225
• Name
  predicted gene 45225

• Feature Type
  pseudogene
• IDs
  MGI:5753801
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr7:25680927-25687885 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, Syntenic

Strain
Comparison

• SNPs within 2kb
  286 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5753801	pseudogene	Chr7:25680927-25687885 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0040550	pseudogene	Chr7:24715699-24722565 (+)
A/J	MGP_AJ_G0040538	pseudogene	Chr7:23861915-23868796 (+)
AKR/J	MGP_AKRJ_G0040463	pseudogene	Chr7:24479868-24488634 (+)
BALB/cJ	MGP_BALBcJ_G0040533	pseudogene	Chr7:24101651-24108542 (+)
C3H/HeJ	MGP_C3HHeJ_G0040165	pseudogene	Chr7:24892660-24900687 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0041175	pseudogene	Chr7:25341403-25348363 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0037428	pseudogene	Chr7:25189216-25198922 (+)
CAST/EiJ	no annotation
CBA/J	MGP_CBAJ_G0040133	pseudogene	Chr7:26244370-26251257 (+)
DBA/2J	MGP_DBA2J_G0040336	pseudogene	Chr7:23762405-23992904 (+)
FVB/NJ	MGP_FVBNJ_G0040280	pseudogene	Chr7:23791643-23798522 (+)
LP/J	MGP_LPJ_G0040373	pseudogene	Chr7:24798684-24805550 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0040273	pseudogene	Chr7:25968863-25975763 (+)
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0038896	pseudogene	Chr7:18751509-18759168 (+)
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0039466	pseudogene	Chr7:24343862-24351656 (+)

Homology

• Gene Tree
  Gm45225
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Gm45225
• Find Mice (IMSR)
  1 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  17

• Ensembl
  ENSMUSG00000108589 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000108589	Ensembl Gene Model | MGI Sequence Detail	6959	C57BL/6J
transcript	ENSMUST00000206852	Ensembl | MGI Sequence Detail	1139	Not Applicable

References

• Summaries
  All 6

  Phenotypes 4
• Earliest
  J:247967 Kumar R, et al., Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice. PLoS One. 2017;12(3):e0174355
• Latest
  J:350361 Hamilton MC, et al., Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic mice compared to Cyp2b-null mice is relieved by a high-fat diet (HFD). Food Chem Toxicol. 2021 Jun;152:112175