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Krt85 Gene Detail
Summary
  • Symbol
    Krt85
  • Name
    keratin 85
  • Synonyms
    Hb5, Krt2-18
  • Feature Type
    protein coding gene
  • IDs
    MGI:1859268
    NCBI Gene: 53622
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr15:101413801-101422054 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, Syntenic
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    67 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1859268
 protein coding gene Chr15:101413569-101422054 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRT85, keratin 85
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT85, keratin 85
  • Synonyms
    ECTD4, Hb-5, HB5, hHb5, K85, KRTHB5
  • Links
    NCBI Gene ID: 3891
    neXtProt AC: NX_P78386
    UniProt: P78386

  • Chr Location
    12q13.13; chr12:52360006-52367481 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human KRT85 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    6
  • Tissues
    3
  • cDNA Data
    4
  • Literature Summary
    6
Sequences &
Gene Models
less
  • All Sequences
    15
  • RefSeq
    2
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000116336 Ensembl Gene Model | MGI Sequence Detail 8254 C57BL/6J ±  kb
transcript ENSMUST00000230067 Ensembl | MGI Sequence Detail 2359 Not Applicable  
polypeptide ENSMUSP00000155398 Ensembl | MGI Sequence Detail 507 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    Genomic 9
    cDNA 4
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145921, MGI:2146253, MGI:6155060
References
more
  • Summaries
    All 29
    Developmental Gene Expression 6
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:74117 Montenegro MA, et al., Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting. J Craniofac Genet Dev Biol. 2000 Jul-Sep;20(3):137-43
  • Latest
    J:290212 Noto M, et al., Sox13 is a novel early marker for hair follicle development. Biochem Biophys Res Commun. 2019 Feb 19;509(4):862-868
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory