Rr124 Other Genome Feature Detail

Summary

• Symbol
  Rr124
• Name
  regulatory region 124
• Synonyms
  CNS2

• Feature Type
  enhancer
• IDs
  MGI:6838412

Location &
Maps

• Sequence Map
  ChrX:7450192-7450739 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• Rr124 deletion coordinates: GRCm39:chrX:7450192-7450739

• Genetic Map
  Chromosome X, Syntenic

Strain
Comparison

• SNPs within 2kb
  75 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:305560 Dikiy S, et al., A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance. Immunity. 2021 May 11;54(5):931-946.e11
• Latest
  J:342283 Zong X, et al., Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity. J Exp Med. 2021 Aug 2;218(8)