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am Gene Detail
Summary
  • Symbol
    am
  • Name
    amputated
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:88001
    NCBI Gene: 11697
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    33 phenotypes from 1 allele in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result in severe skeletal defects that lead to neonatal death.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-1290
References
more
  • Summaries
    All 10
    Phenotypes 9
  • Earliest
    J:6007 Flint OP, et al., Cell interactions in the developing somite; in vivo comparisons between amputated (AM/AM) and normal mouse embryos. J Cell Sci. 1978 Jun;31:275-91
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory