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Crip1 Gene Detail
Summary
  • Symbol
    Crip1
  • Name
    cysteine-rich protein 1
  • Synonyms
    Crip, CRP1
  • Feature Type
    protein coding gene
  • IDs
    MGI:88501
    NCBI Gene: 12925
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113115632-113117499 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.59 cM
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88501
 protein coding gene Chr12:113109936-113117499 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020173
 protein coding gene Chr12:115642359-115649905 (+)
A/J MGP_AJ_G0020129
 protein coding gene Chr12:111164499-111172037 (+)
AKR/J MGP_AKRJ_G0020104
 protein coding gene Chr12:114395726-114403280 (+)
BALB/cJ MGP_BALBcJ_G0020114
 protein coding gene Chr12:111630017-111637555 (+)
C3H/HeJ MGP_C3HHeJ_G0019916
 protein coding gene Chr12:114917656-114925201 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020559
 protein coding gene Chr12:119187733-119195294 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018173
 protein coding gene Chr12:107598426-107606159 (+)
CAST/EiJ MGP_CASTEiJ_G0019456
 protein coding gene Chr12:109762860-109772032 (+)
CBA/J MGP_CBAJ_G0019883
 protein coding gene Chr12:123755720-123763216 (+)
DBA/2J MGP_DBA2J_G0020000
 protein coding gene Chr12:110665633-110673160 (+)
FVB/NJ MGP_FVBNJ_G0019985
 protein coding gene Chr12:109509254-109516801 (+)
LP/J MGP_LPJ_G0020074
 protein coding gene Chr12:115462699-115470253 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020023
 protein coding gene Chr12:126842312-126851149 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020588
 protein coding gene Chr12:113912415-113919957 (+)
PWK/PhJ MGP_PWKPhJ_G0019218
 protein coding gene Chr12:105327555-105335145 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019022
 protein coding gene Chr12:108092428-108100396 (+)
WSB/EiJ MGP_WSBEiJ_G0019516
 protein coding gene Chr12:114826657-114834206 (+)



Homology
more
  • Human Ortholog
    CRIP1, cysteine rich protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CRIP1, cysteine rich protein 1
  • Synonyms
    CRHP, CRIP, CRP-1, CRP1
  • Links
    NCBI Gene ID: 1396
    neXtProt AC: NX_P50238
    UniProt: P50238

  • Chr Location
    14q32.33; chr14:105486317-105488947 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    827
  • Tissues
    61
  • cDNA Data
    111
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 12925 NCBI Gene Model | MGI Sequence Detail 1868 C57BL/6J ±  kb
transcript NM_007763 RefSeq | MGI Sequence Detail 460 ZRU/MplStud  
polypeptide P63254 UniProt | EBI | MGI Sequence Detail 77 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 113
    cDNA 112
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-2144
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:8280 Birkenmeier EH, et al., Developmental regulation of a gene that encodes a cysteine-rich intestinal protein and maps near the murine immunoglobulin heavy chain locus. Proc Natl Acad Sci U S A. 1986 Apr;83(8):2516-20
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory