Csn1s2a MGI Mouse Gene Detail - MGI:88542 - casein alpha s2-like A

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Csn1s2a Gene Detail

Symbol

Csn1s2a
Name

casein alpha s2-like A
Synonyms

Csn1s2a, Csng

Feature Type

protein coding gene
IDs

MGI:88542
NCBI Gene: 12993
Member of

Csn cluster
Alliance

gene page
Transcription Start Sites

32 TSS

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Sequence Map

Chr5:87922426-87936656 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 43.56 cM
Mapping Data

7 experiments

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SNPs within 2kb

409 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates	Select Strains
C57BL/6J	MGI_C57BL6J_88542	protein coding gene	Chr5:87922309-87936657 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029691	protein coding gene	Chr5:88731763-88746374 (+)
A/J	MGP_AJ_G0029658	protein coding gene	Chr5:85115584-85129821 (+)
AKR/J	MGP_AKRJ_G0029604	protein coding gene	Chr5:87932326-87948619 (+)
BALB/cJ	MGP_BALBcJ_G0029667	protein coding gene	Chr5:86027678-86046238 (+)
C3H/HeJ	MGP_C3HHeJ_G0029390	protein coding gene	Chr5:88337073-88352287 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030122	protein coding gene	Chr5:92391450-92406285 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027360	protein coding gene	Chr5:80730406-80744698 (+)
CAST/EiJ	MGP_CASTEiJ_G0028800	protein coding gene	Chr5:87713866-87733582 (+)
CBA/J	MGP_CBAJ_G0029359	protein coding gene	Chr5:95275758-95296346 (+)
DBA/2J	MGP_DBA2J_G0029504	protein coding gene	Chr5:85286570-85300799 (+)
FVB/NJ	MGP_FVBNJ_G0029464	protein coding gene	Chr5:84199101-84213339 (+)
LP/J	MGP_LPJ_G0029592	protein coding gene	Chr5:89143550-89157741 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029493	protein coding gene	Chr5:100339142-100360053 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030155	protein coding gene	Chr5:87492191-87507017 (+)
PWK/PhJ	MGP_PWKPhJ_G0028519	protein coding gene	Chr5:84272288-84286658 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028357	protein coding gene	Chr5:86905468-86919848 (+)
WSB/EiJ	MGP_WSBEiJ_G0028879	protein coding gene	Chr5:87884662-87898860 (+)

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Human Ortholog

CSN1S2AP, casein alpha s2 like A, pseudogene

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CSN1S2AP, casein alpha s2 like A, pseudogene
Synonyms

CSN1S2A
Links

HGNC:20230

NCBI Gene ID: 286828
Chr Location

4q13.3; chr4:70067386-70085290 (+) GRCh38

MGI Vertebrate Homology

Csn1s2a stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: CSN1S2AP
Gene Tree

Csn1s2a

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Phenotype Summary

11 phenotype references

All Mutations and Alleles

10
Chemically induced (other)

2
Endonuclease-mediated

2
Radiation induced

1
Spontaneous

1
Targeted

4
Genomic Mutations

4 involving Csn1s2a
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

25 strains or lines available

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All GO Annotations

4
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

901
Tissues

21
cDNA Data

9
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

56
RefSeq

10
UniProt

5
CCDS

CCDS39132.1, CCDS80318.1, CCDS84900.1, CCDS84901.1

Ensembl

ENSMUSG00000061937 (Evidence)
NCBI Gene

12993

Representative Sequences				Length	Strain/Species	Flank
	genomic	ENSMUSG00000061937	Ensembl Gene Model \| MGI Sequence Detail	14231	C57BL/6J	± kb
	transcript	ENSMUST00000076379	Ensembl \| MGI Sequence Detail	920	Not Applicable
	polypeptide	ENSMUSP00000075716	Ensembl \| MGI Sequence Detail	184	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000006204 alpha-S2-casein-like A

(term hierarchy)
InterPro Domains

IPR011175 Alpha-s2 casein

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All nucleic 20

Genomic 8

cDNA 12

Microarray probesets 5

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MGD-MRK-2200

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Summaries

All 37

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 11
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Csn1s2a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr46897	Chr5:87922411-87922432 (+)	-4 bp
Tssr46898	Chr5:87922786-87922795 (+)	365 bp
Tssr46899	Chr5:87923158-87923168 (+)	737 bp
Tssr46900	Chr5:87923625-87923641 (+)	1,207 bp
Tssr46901	Chr5:87923643-87923661 (+)	1,226 bp
Tssr46902	Chr5:87923670-87923677 (+)	1,248 bp
Tssr46903	Chr5:87925070-87925086 (+)	2,652 bp
Tssr46904	Chr5:87925294-87925303 (+)	2,873 bp
Tssr46905	Chr5:87925911-87925918 (+)	3,489 bp
Tssr46906	Chr5:87926022-87926045 (+)	3,608 bp
Tssr46907	Chr5:87926808-87926820 (+)	4,388 bp
Tssr46908	Chr5:87927855-87927885 (+)	5,444 bp
Tssr46909	Chr5:87927962-87927991 (+)	5,551 bp
Tssr46910	Chr5:87928011-87928014 (+)	5,587 bp
Tssr46911	Chr5:87928815-87928818 (+)	6,391 bp
Tssr1530	Chr5:87929634-87929635 (+)	7,209 bp
Tssr46912	Chr5:87929640-87929664 (+)	7,226 bp
Tssr46913	Chr5:87929666-87929671 (+)	7,243 bp
Tssr46914	Chr5:87929675-87929682 (+)	7,253 bp
Tssr46915	Chr5:87929686-87929722 (+)	7,278 bp
Tssr46916	Chr5:87932398-87932399 (+)	9,973 bp
Tssr46917	Chr5:87932413-87932428 (+)	9,995 bp
Tssr46918	Chr5:87933134-87933148 (+)	10,715 bp
Tssr46919	Chr5:87934441-87934462 (+)	12,026 bp
Tssr46920	Chr5:87934466-87934496 (+)	12,055 bp
Tssr46921	Chr5:87934497-87934508 (+)	12,077 bp
Tssr46922	Chr5:87934510-87934513 (+)	12,086 bp
Tssr46923	Chr5:87934534-87934539 (+)	12,111 bp
Tssr46924	Chr5:87936403-87936420 (+)	13,986 bp
Tssr46925	Chr5:87936557-87936567 (+)	14,136 bp
Tssr46926	Chr5:87936591-87936606 (+)	14,173 bp
Tssr46927	Chr5:87936617-87936627 (+)	14,196 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24