About   Help   FAQ
Frg1 Gene Detail
Summary
  • Symbol
    Frg1
  • Name
    FSHD region gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:893597
    NCBI Gene: 14300
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:41850496-41870111 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 23.89 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    378 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_893597
 protein coding gene Chr8:41842218-41870179 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033563
 protein coding gene Chr8:40233957-40255258 (-)
A/J MGP_AJ_G0033546
 protein coding gene Chr8:38716479-38739729 (-)
AKR/J MGP_AKRJ_G0033469
 protein coding gene Chr8:39872328-39893199 (-)
BALB/cJ MGP_BALBcJ_G0033541
 protein coding gene Chr8:38825624-38846461 (-)
C3H/HeJ MGP_C3HHeJ_G0033251
 protein coding gene Chr8:40263359-40282873 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034057
 protein coding gene Chr8:41759586-41779178 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031006
 protein coding gene Chr8:35354001-35373820 (-)
CAST/EiJ MGP_CASTEiJ_G0032579
 protein coding gene Chr8:39768433-39788806 (-)
CBA/J MGP_CBAJ_G0033229
 protein coding gene Chr8:43480326-43508279 (-)
DBA/2J MGP_DBA2J_G0033383
 protein coding gene Chr8:38533652-38553204 (-)
FVB/NJ MGP_FVBNJ_G0033327
 protein coding gene Chr8:38125683-38145975 (-)
LP/J MGP_LPJ_G0033472
 protein coding gene Chr8:40274940-40296767 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033369
 protein coding gene Chr8:43268894-43289524 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034075
 protein coding gene Chr8:40033290-40054879 (-)
PWK/PhJ MGP_PWKPhJ_G0032288
 protein coding gene Chr8:38084815-38104723 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032120
 protein coding gene Chr8:39194153-39216775 (-)
WSB/EiJ MGP_WSBEiJ_G0032694
 protein coding gene Chr8:40236905-40259626 (-)



Homology
more
  • Human Ortholog
    FRG1, FSHD region gene 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FRG1, FSHD region gene 1
  • Synonyms
    FRG1A, FSG1
  • Links
    NCBI Gene ID: 2483
    neXtProt AC: NX_Q14331
    UniProt: Q14331

  • Chr Location
    4q35.2; chr4:189940855-189963202 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    849
  • Tissues
    51
  • cDNA Data
    65
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031590 Ensembl Gene Model | MGI Sequence Detail 19616 C57BL/6J ±  kb
transcript ENSMUST00000033999 Ensembl | MGI Sequence Detail 1039 Not Applicable  
polypeptide ENSMUSP00000033999 Ensembl | MGI Sequence Detail 258 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    Genomic 7
    cDNA 65
    Primer pair 5
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:40667 Grewal PK, et al., The mouse homolog of FRG1, a candidate gene for FSHD, maps proximal to the myodystrophy mutation on chromosome 8. Mamm Genome. 1997 Jun;8(6):394-8
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory