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Galnt4 Gene Detail
Summary
  • Symbol
    Galnt4
  • Name
    polypeptide N-acetylgalactosaminyltransferase 4
  • Synonyms
    ppGaNTase-T4
  • Feature Type
    protein coding gene
  • IDs
    MGI:894692
    NCBI Gene: 14426
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:98944021-98949109 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 51.06 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894692
 protein coding gene Chr10:98943997-98949109 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017684
 protein coding gene Chr10:100913965-100919053 (+)
A/J MGP_AJ_G0017663
 protein coding gene Chr10:97272616-97277704 (+)
AKR/J MGP_AKRJ_G0017623
 protein coding gene Chr10:100060713-100065801 (+)
BALB/cJ MGP_BALBcJ_G0017627
 protein coding gene Chr10:97544277-97549365 (+)
C3H/HeJ MGP_C3HHeJ_G0017450
 protein coding gene Chr10:100076998-100082086 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018083
 protein coding gene Chr10:104394058-104399146 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015764
 protein coding gene Chr10:92701608-92706736 (+)
CAST/EiJ MGP_CASTEiJ_G0017013
 protein coding gene Chr10:100142012-100147100 (+)
CBA/J MGP_CBAJ_G0017419
 protein coding gene Chr10:108490830-108495918 (+)
DBA/2J MGP_DBA2J_G0017525
 protein coding gene Chr10:96355566-96360654 (+)
FVB/NJ MGP_FVBNJ_G0017518
 protein coding gene Chr10:95570182-95575270 (+)
LP/J MGP_LPJ_G0017599
 protein coding gene Chr10:101493043-101498131 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017548
 protein coding gene Chr10:109763930-109769018 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018121
 protein coding gene Chr10:99963965-99969053 (+)
PWK/PhJ MGP_PWKPhJ_G0016795
 protein coding gene Chr10:96486188-96491267 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016584
 protein coding gene Chr10:98875423-98880506 (+)
WSB/EiJ MGP_WSBEiJ_G0017073
 protein coding gene Chr10:99974166-99979254 (+)



Homology
more
  • Human Ortholog
    GALNT4, polypeptide N-acetylgalactosaminyltransferase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GALNT4, polypeptide N-acetylgalactosaminyltransferase 4
  • Synonyms
    GALNAC-T4, GALNACT4
  • Links
    NCBI Gene ID: 8693
    neXtProt AC: NX_Q8N4A0
    UniProt: Q8N4A0

  • Chr Location
    12q21.33; chr12:89519412-89524796 (-)  GRCh38
  • Human Ortholog
    POC1B-GALNT4, POC1B-GALNT4 readthrough
  • Synonyms
    GalNAc-T4, GALNT4
  • Links
    NCBI Gene ID: 100528030
    neXtProt AC: NX_Q8N4A0

  • Chr Location
    12q21.33; chr12:89519408-89526262 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    6 phenotype references
An unpublished knockout mutation is reported to have no overt phenotypic consequences.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    822
  • Tissues
    113
  • cDNA Data
    44
  • Literature Summary
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090035 Ensembl Gene Model | MGI Sequence Detail 5089 C57BL/6J ±  kb
transcript ENSMUST00000161240 Ensembl | MGI Sequence Detail 5089 Not Applicable  
polypeptide ENSMUSP00000125315 Ensembl | MGI Sequence Detail 578 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 44
    Primer pair 4
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2143775
References
more
  • Summaries
    All 42
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:324578 Ye Z, et al., GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis. J Mol Cell Cardiol. 2022 Apr;165:54-63
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory