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Eif3a Gene Detail
Summary
  • Symbol
    Eif3a
  • Name
    eukaryotic translation initiation factor 3, subunit A
  • Synonyms
    A830012B05Rik, Csma, Eif3, Eif3s10
  • Feature Type
    protein coding gene
  • IDs
    MGI:95301
    NCBI Gene: 13669
  • Alliance
    gene page
  • Transcription Start Sites
    39 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:60749555-60779096 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 56.52 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    534 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95301
 protein coding gene Chr19:60749554-60779131 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025295
 protein coding gene Chr19:61361740-61393661 (-)
A/J MGP_AJ_G0025271
 protein coding gene Chr19:58364218-58394019 (-)
AKR/J MGP_AKRJ_G0025240
 protein coding gene Chr19:60183215-60214792 (-)
BALB/cJ MGP_BALBcJ_G0025266
 protein coding gene Chr19:58446763-58476174 (-)
C3H/HeJ MGP_C3HHeJ_G0025026
 protein coding gene Chr19:60427336-60457746 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025709
 protein coding gene Chr19:62817041-62846603 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023121
 protein coding gene Chr19:57198016-57227175 (-)
CAST/EiJ MGP_CASTEiJ_G0024491
 protein coding gene Chr19:60532191-60563787 (-)
CBA/J MGP_CBAJ_G0025006
 protein coding gene Chr19:65878471-65912238 (-)
DBA/2J MGP_DBA2J_G0025138
 protein coding gene Chr19:58146262-58177619 (-)
FVB/NJ MGP_FVBNJ_G0025099
 protein coding gene Chr19:57817579-57847710 (-)
LP/J MGP_LPJ_G0025224
 protein coding gene Chr19:61199640-61230507 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025132
 protein coding gene Chr19:65075561-65105201 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025767
 protein coding gene Chr19:60430096-60460190 (-)
PWK/PhJ MGP_PWKPhJ_G0024239
 protein coding gene Chr19:58092454-58122857 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024042
 protein coding gene Chr19:59076471-59107074 (-)
WSB/EiJ MGP_WSBEiJ_G0024561
 protein coding gene Chr19:60534985-60565899 (-)



Homology
more
  • Human Ortholog
    EIF3A, eukaryotic translation initiation factor 3 subunit A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF3A, eukaryotic translation initiation factor 3 subunit A
  • Synonyms
    EIF3, eIF3-p170, EIF3S10, eIF3-theta, P167, p180, p185, TIF32
  • Links
    NCBI Gene ID: 8661
    neXtProt AC: NX_Q14152
    UniProt: Q14152

  • Chr Location
    10q26.11; chr10:119033670-119080817 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    38
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    753
  • Tissues
    29
  • cDNA Data
    23
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024991 Ensembl Gene Model | MGI Sequence Detail 29542 C57BL/6J ±  kb
transcript ENSMUST00000025955 Ensembl | MGI Sequence Detail 5125 Not Applicable  
polypeptide ENSMUSP00000025955 Ensembl | MGI Sequence Detail 1344 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000006973 eukaryotic translation initiation factor 3 subunit A
    (term hierarchy)
  • InterPro Domains
    IPR027512 Eukaryotic translation initiation factor 3 subunit A
    IPR000717 Proteasome component (PCI) domain
  • GlyGen
    P23116 6 sites, 2 N-linked glycans (3 sites), 1 O-linked glycan (3 sites)
Molecular
Reagents
less
  • All nucleic 24
    Genomic 1
    cDNA 23

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-2196, MGD-MRK-9334, MGI:2443799, MGI:88538
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 9
  • Earliest
    J:11284 Joswig G, et al., Murine cDNAs coding for the centrosomal antigen centrosomin A. J Cell Sci. 1991 Jan;98(Pt 1):37-43
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory