Fv5 Gene Detail

Summary

• Symbol
  Fv5
• Name
  Friend virus P-induced early anemia, polycythemia susceptibility
• Synonyms
  Fv-5

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95599
  NCBI Gene: 108109
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

Alleles at this locus determine response to Friend Virus-P (VF-P) infection. DBA/2, BALB/c and AKR (p allele) show early polycythemia (high hematocrit); CBA/J and C3H (a allele) show early anemic response (low hematocrit). Heterozygotes have slight polycythemia with intermediate hematocrits.

Sequences &
Gene Models

• NCBI Gene
  108109

Other
Accession IDs

MGD-MRK-9899, MGD-MRK-9905

References

• Summaries
  All 4
• Earliest
  J:6744 Shibuya T, et al., A host gene controlling early anaemia or polycythaemia induced by Friend erythroleukaemia virus. Nature. 1982 Apr 8;296(5857):577-9
• Latest
  J:6813 Shibuya T, et al., Erythroleukemia induction by Friend leukemia virus. A host gene locus controlling early anemia or polycythemia and the rate of proliferation of late erythroid cells. J Exp Med. 1982 Aug 1;156(2):398-414