Fv6 Gene Detail

Summary

• Symbol
  Fv6
• Name
  Friend virus susceptibility 6
• Synonyms
  Fv-6

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95600
  NCBI Gene: 107451
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

This locus controls susceptibility to early erythroleukemia induction by helper virus-independent NB-tropic Friend leukemia virus. BALB/c, NFS and C3H/He carry the susceptibility (s) allele; DBA/2, DBA/1, C57BL/6, C57BL/10, C57L, CBA/N and AKR/N carry the dominant resistant ( r) allele.

Sequences &
Gene Models

• NCBI Gene
  107451

Other
Accession IDs

MGD-MRK-9900, MGD-MRK-9906

References

• Summaries
  All 4
• Earliest
  J:6583 Ruscetti S, et al., Friend murine leukemia virus-induced leukemia is associated with the formation of mink cell focus-inducing viruses and is blocked in mice expressing endogenous mink cell focus-inducing xenotropic viral envelope genes. J Exp Med. 1981 Sep 1;154(3):907-20
• Latest
  J:6978 Shibuya T, et al., Host control of susceptibility to erythroleukemia and to the types of leukemia induced by Friend murine leukemia virus: initial and late stages. Cell. 1982 Dec;31(2 Pt 1):483-93