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H2-Q9 Gene Detail
Summary
  • Symbol
    H2-Q9
  • Name
    histocompatibility 2, Q region locus 9
  • Synonyms
    H-2Q9, Ped, Qa-9, Qa9
  • Feature Type
    protein coding gene
  • IDs
    MGI:95938
    NCBI Gene: 110558
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:35752074-35756659 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, Syntenic
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • Strain Annotations
    1
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95938
 protein coding gene Chr17:35752074-35756659 (+)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Mutations,
Alleles, and
Phenotypes
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This locus controls a lymphocyte antigen on T- and B-cells of spleen, lymph nodes and bone marrow, but not thymus. Antigen is present (a allele) in C57BL/6, C57BL/10, C57L and 129/J; other strains tested are negative (b allele). Expression level is affected by alleles carried at B2m and H2-D1 loci.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    30
  • Tissues
    9
  • cDNA Data
    2
  • Literature Summary
    4
  • Other Mouse Links
    GEO
Sequences &
Gene Models
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  • All Sequences
    16
  • RefSeq
    6
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic 110558 NCBI Gene Model | MGI Sequence Detail 4586 C57BL/6J ±  kb
transcript NM_001201460 RefSeq | MGI Sequence Detail 1539 ZRU/MplStud  
polypeptide P14431 UniProt | EBI | MGI Sequence Detail 200 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • InterPro Domains
    IPR050208 Antigen-presenting and immune regulatory MHC class I-related
    IPR003597 Immunoglobulin C1-set
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    IPR011162 MHC classes I/II-like antigen recognition protein
    IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
    IPR011161 MHC class I-like antigen recognition-like
    IPR037055 MHC class I-like antigen recognition-like superfamily
  • GlyGen
    P14431 1 site
Molecular
Reagents
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  • All nucleic 22
    Genomic 15
    cDNA 2
    Primer pair 1
    Other 4
Other
Accession IDs
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MGD-MRK-10421, MGD-MRK-10534, MGD-MRK-13710, MGD-MRK-13717, MGD-MRK-13728
References
more
  • Summaries
    All 28
    Developmental Gene Expression 4
    Gene Ontology 4
  • Earliest
    J:20104 Steinmetz M, et al., Clusters of genes encoding mouse transplantation antigens. Cell. 1982 Mar;28(3):489-98
  • Latest
    J:177498 Martinez-Naves E, et al., Recognition of the ligand-type specificity of classical and non-classical MHC I proteins. FEBS Lett. 2011 Nov 4;585(21):3478-84
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory