H3 Gene Detail

Summary

• Symbol
  H3
• Name
  histocompatibility 3
• Synonyms
  H-3

• Feature Type
  protein coding gene
• IDs
  MGI:95977
  NCBI Gene: 109741
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  22 experiments

Mutations,
Alleles, and
Phenotypes

This locus was identified in developing congenic strains differing in resistance to transplantable tumors. Antigen is recognized by cytotoxic T lymphocyte response, which is H2-D1-restricted. C57BL/10 carries the a allele and B10.LP carries the b allele.

Sequences &
Gene Models

• NCBI Gene
  109741

Other
Accession IDs

MGD-MRK-10449, MGD-MRK-10573

References

• Summaries
  All 47
• Earliest
  J:119 Snell GD, et al., H-3, a 5th chromosome histocompatibility locus identified in the mouse by tumor transplantation. Proc Am Assoc Cancer Res. 1955;1(1):46 (Abstr.)
• Latest
  J:220372 Kang H, et al., Dynamics of histone H3 phosphorylation at threonine 3 during meiotic maturation in mouse oocytes. Biochem Biophys Res Commun. 2015 Mar 6;458(2):280-6