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Hmga1b Gene Detail
Summary
  • Symbol
    Hmga1b
  • Name
    high mobility group AT-hook 1B
  • Synonyms
    ENSMUSG00000041059, Hmga1-rs1, Hmgi-rs1
  • Feature Type
    protein coding gene
  • IDs
    MGI:96161
    NCBI Gene: 111241
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120653620-120655218 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.51 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    116 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96161
 protein coding gene Chr11:120653620-120655245 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019527
 protein coding gene Chr11:125250658-125250777 (+)
A/J MGP_AJ_G0023379
 protein coding gene Chr17:26015412-26025540 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0023384
 protein coding gene Chr17:26293936-26300632 (+)
C3H/HeJ MGP_C3HHeJ_G0023145
 protein coding gene Chr17:26551265-26559225 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019918
 protein coding gene Chr11:129041636-129045924 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021301
 protein coding gene Chr17:23405984-23410084 (+)
CAST/EiJ MGP_CASTEiJ_G0022646
 protein coding gene Chr17:26502321-26508167 (+)
CBA/J MGP_CBAJ_G0023119
 protein coding gene Chr17:28943635-28953782 (+)
DBA/2J MGP_DBA2J_G0019359
 protein coding gene Chr11:119045437-119045556 (+)
FVB/NJ MGP_FVBNJ_G0023220
 protein coding gene Chr17:25362182-25371367 (+)
LP/J MGP_LPJ_G0023328
 protein coding gene Chr17:27128218-27138345 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023238
 protein coding gene Chr17:28442653-28446855 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023868
 protein coding gene Chr17:26582528-26592257 (+)
PWK/PhJ MGP_PWKPhJ_G0022396
 protein coding gene Chr17:24366510-24370805 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022214
 protein coding gene Chr17:24588021-24593362 (+)
WSB/EiJ MGP_WSBEiJ_G0018882
 protein coding gene Chr11:123955448-123955567 (+)



Homology
more
  • Human Ortholog
    HMGA1, high mobility group AT-hook 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HMGA1, high mobility group AT-hook 1
  • Synonyms
    HMGA1A, HMGIY, HMG-R
  • Links
    NCBI Gene ID: 3159
    neXtProt AC: NX_P17096
    UniProt: P17096

  • Chr Location
    6p21.31; chr6:34236873-34246231 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human HMGA1 associations

Human Disease Mouse Models
      
IDs
 View 2 models
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1066
  • Tissues
    65
  • cDNA Data
    1
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 111241 NCBI Gene Model | MGI Sequence Detail 1599 C57BL/6J ±  kb
transcript NM_001166476 RefSeq | MGI Sequence Detail 1599 ZRU/MplStud  
polypeptide NP_001159948 RefSeq | MGI Sequence Detail 107 ZRU/MplStud  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
Other
Accession IDs
less
MGD-MRK-10797, MGI:3708561, MGI:5908446
References
more
  • Summaries
    All 16
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:9471 Johnson KR, et al., Complete murine cDNA sequence, genomic structure, and tissue expression of the high mobility group protein HMG-I(Y). J Biol Chem. 1988 Dec 5;263(34):18338-42
  • Latest
    J:263646 Horiuchi K, et al., Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Cell Rep. 2018 Apr 3;23(1):143-155
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory