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Hoxc5 Gene Detail
Summary
  • Symbol
    Hoxc5
  • Name
    homeobox C5
  • Synonyms
    Hox-3.4, Hox-6.2
  • Feature Type
    protein coding gene
  • IDs
    MGI:96196
    NCBI Gene: 15424
  • Member of
    Hoxc cluster
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102922440-102925861 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 58.07 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    76 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_96196
 protein coding gene Chr15:102875878-102925861 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022428
 protein coding gene Chr15:105202997-105252732 (+)
A/J MGP_AJ_G0022390
 protein coding gene Chr15:101046116-101096527 (+)
AKR/J MGP_AKRJ_G0022365
 protein coding gene Chr15:104115387-104166601 (+)
BALB/cJ MGP_BALBcJ_G0022394
 protein coding gene Chr15:101094131-101144648 (+)
C3H/HeJ MGP_C3HHeJ_G0022161
 protein coding gene Chr15:104192035-104244732 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022843
 protein coding gene Chr15:109097601-109148561 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020366
 protein coding gene Chr15:96815610-96865806 (+)
CAST/EiJ MGP_CASTEiJ_G0021687
 protein coding gene Chr15:105065340-105119033 (+)
CBA/J MGP_CBAJ_G0022130
 protein coding gene Chr15:112931523-112984049 (+)
DBA/2J MGP_DBA2J_G0022261
 protein coding gene Chr15:100316445-100367112 (+)
FVB/NJ MGP_FVBNJ_G0022237
 protein coding gene Chr15:99386076-99436047 (+)
LP/J MGP_LPJ_G0022330
 protein coding gene Chr15:105338137-105389328 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022259
 protein coding gene Chr15:116446797-116497695 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022855
 protein coding gene Chr15:104154230-104205848 (+)
PWK/PhJ MGP_PWKPhJ_G0021427
 protein coding gene Chr15:100495708-100546812 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021259
 protein coding gene Chr15:103984041-104036577 (+)
WSB/EiJ MGP_WSBEiJ_G0021737
 protein coding gene Chr15:104768887-104818988 (+)



Homology
more
  • Human Ortholog
    HOXC5, homeobox C5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HOXC5, homeobox C5
  • Synonyms
    CP11, HOX3, HOX3D
  • Links
    NCBI Gene ID: 3222
    neXtProt AC: NX_Q00444
    UniProt: Q00444

  • Chr Location
    12q13.13; chr12:54016888-54035361 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from multigenic genotypes
    39 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1064
  • Tissues
    225
  • cDNA Data
    21
  • Literature Summary
    58
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 15424 NCBI Gene Model | MGI Sequence Detail 3422 C57BL/6J ±  kb
transcript NM_175730 RefSeq | MGI Sequence Detail 2730 ZRU/MplStud  
polypeptide P32043 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 45
    Genomic 9
    cDNA 23
    Primer pair 7
    Other 6

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-10842, MGD-MRK-10866, MGD-MRK-10897, MGI:2145954
References
more
  • Summaries
    All 123
    Developmental Gene Expression 58
    Diseases 1
    Gene Ontology 7
    Phenotypes 39
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:354191 Kc R, et al., Multimodal Hox5 activity generates motor neuron diversity. Commun Biol. 2024 Sep 17;7(1):1166
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory