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Igk-J Complex/Cluster/Region Detail
Summary
  • Symbol
    Igk-J
  • Name
    immunoglobulin kappa chain, joining region
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:96497
    NCBI Gene: 16073
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 6, Syntenic
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • RFLP
    7
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    21 phenotypes from multigenic genotypes
    37 phenotype references
Mice homozygous for various knock-in alleles exhibit abnormal immune system morphology and function.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    12
  • Tissues
    12
  • cDNA Data
    1
  • Literature Summary
    1
  • Other Mouse Links
    GEO
Sequences &
Gene Models
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  • All Sequences
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic M15559 GenBank | ENA | DDBJ | MGI Sequence Detail 1430 C.C58 M75* ±  kb
For the selected sequence
Molecular
Reagents
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  • All nucleic 120
    Genomic 53
    cDNA 62
    Other 5
Other
Accession IDs
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MGD-MRK-11296
References
more
  • Summaries
    All 87
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 37
  • Earliest
    J:6069 Seidman JG, et al., The arrangement and rearrangement of antibody genes. Nature. 1978 Dec 21-28;276(5690):790-5
  • Latest
    J:300457 Elsner RA, et al., IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019 Nov 26;29(9):2796-2809.e5
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory