Igl Complex/Cluster/Region Detail

Summary

• Symbol
  Igl
• Name
  immunoglobulin lambda chain complex
• Synonyms
  Igl-x

• Feature Type
  complex/cluster/region
• IDs
  MGI:96526
  NCBI Gene: 111519

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic
• Mapping Data
  27 experiments

Strain
Comparison

• RFLP
  2

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  14 phenotypes from multigenic genotypes
  7 phenotype references
  

• All Mutations and Alleles
  8
• Endonuclease-mediated
  2
• Targeted
  5
• Transgenic
  1
• Genomic Mutations
  2 involving Igl
• Find Mice (IMSR)
  3 strains or lines available

Expression

• Other Mouse Links
  GEO
• Other Vertebrate Links
  Xenbase igl

Sequences &
Gene Models

• All Sequences
  1
• RefSeq
  1

• NCBI Gene
  111519

Molecular
Reagents

• All nucleic 18

  Genomic 17

  Other 1

Other
Accession IDs

MGD-MRK-11331, MGD-MRK-11338

References

• Summaries
  All 71

  Phenotypes 7
• Earliest
  J:31041 Westermark P, et al., Coexistence of protein AA and immunoglobulin light-chain fragments in amyloid fibrils. Scand J Immunol. 1976;5(1-2):31-6
• Latest
  J:234833 McGuire AT, et al., Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice. Nat Commun. 2016;7:10618