Lyx3 Gene Detail

Summary

• Symbol
  Lyx3
• Name
  lymphocyte antigen X 3
• Synonyms
  Lyx-3

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96896
  NCBI Gene: 104164
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome X, Syntenic

Mutations,
Alleles, and
Phenotypes

This locus controls antigen present on T-cells of SJL, C57BL/6 and AKR and absent from T-cells of DBA/2, BALB/c, C3H/He and A/J. Immune response to denatured DNA is high (and dominant) in strains positive for antigen and low in strains negative for it.

Sequences &
Gene Models

• NCBI Gene
  104164

Other
Accession IDs

MGD-MRK-12079, MGD-MRK-12082

References

• Summaries
  All 4
• Earliest
  J:5456 Mozes E, et al., Linkage between immune response potential to DNA and X chromosome. Nature. 1974 May 10;249(453):167-8
• Latest
  J:5793 Zeicher M, et al., Lymphocytes alloantigens associated with X-chromosome-linked immune response genes. Proc Natl Acad Sci U S A. 1977 Feb;74(2):721-4