mea Gene Detail

Summary

• Symbol
  mea
• Name
  meander tail

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96956
  NCBI Gene: 17255
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotypes from 3 alleles in 4 genetic backgrounds
  2 images
  16 phenotype references
  

• All Mutations and Alleles
  3
• Spontaneous
  3
• Find Mice (IMSR)
  2 strains or lines available

Mice homozygous for this mutation display variable severity of tail kinks, variable ankylosis or fusion of the caudal vertebrae, and abnormal anterior cerebellum morphology including loss of granule cells and ectopic Purkinje cells.

Sequences &
Gene Models

• NCBI Gene
  17255

Other
Accession IDs

MGD-MRK-12182

References

• Summaries
  All 17

  Phenotypes 16
• Earliest
  J:5951 Hollander WF, et al., Meander tail: a recessive mutant located in chromosome 4 of the mouse. J Hered. 1977 Nov-Dec;68(6):403-6
• Latest
  J:109119 Manzini MC, et al., The stop signal revised: immature cerebellar granule neurons in the external germinal layer arrest pontine mossy fiber growth. J Neurosci. 2006 May 31;26(22):6040-51