Msz Gene Detail

Summary

• Symbol
  Msz
• Name
  resistance to diabetes induction by MSz

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97170
  NCBI Gene: 107787
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

Multiple doses of streptozotocin (MSz) can induce diabetes in male mice. Susceptibility to diabetes thus induced varies widely among inbred strains. The BALB/cByJ substrain carries a recessive susceptibility allele; but BALB/cJ carries a dominant resistance allele. The locus is not linked to H2.

Sequences &
Gene Models

• NCBI Gene
  107787

Other
Accession IDs

MGD-MRK-12572

References

• Summaries
  All 3
• Earliest
  J:13074 Mackensen JA, "Open eyelids" in newborn mice. J Hered. 1960;51(4):188-190
• Latest
  J:9696 Leiter EH, et al., Genetic and environmental control of diabetes induction by multi-dose streptozotocin in two BALB/c substrains. Diabetes Res. 1988 Sep;9(1):5-10