Mylf-ps Pseudogene Detail

Summary

• Symbol
  Mylf-ps
• Name
  myosin light chain, alkali, fast skeletal muscle, pseudogene
• Synonyms
  alkali myosin light chains MLC1f/MLC3f pseudogene

• Feature Type
  pseudogene
• IDs
  MGI:97270
  NCBI Gene: 17902
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr12:101188256-101188676 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 12, 51.23 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  48 from dbSNP Build 142
• Strain Annotations
  1
• RFLP
  3

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_97270	pseudogene	Chr12:101187969-101188677 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Mylf-ps
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (other)
  1
• Genomic Mutations
  1 involving Mylf-ps
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  6
• RefSeq
  1

• Ensembl
  ENSMUSG00000113178 (Evidence)
• NCBI Gene
  17902

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000113178	Ensembl Gene Model | MGI Sequence Detail	421	C57BL/6J
transcript	ENSMUST00000222174	Ensembl | MGI Sequence Detail	421	Not Applicable

Molecular
Reagents

• All nucleic 7

  Genomic 5

  cDNA 1

  Other 1

Other
Accession IDs

MGD-MRK-12768

References

• Summaries
  All 9

  Phenotypes 2
• Earliest
  J:7607 Robert B, et al., A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus corresponds to a related pseudogene. Cell. 1984 Nov;39(1):129-40
• Latest
  J:329342 Sitbon YH, et al., Ablation of the N terminus of cardiac essential light chain promotes the super-relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice. FEBS J. 2020 Sep;287(18):3989-4004

TSS for Mylf-ps:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr117357	Chr12:101188373-101188388 (-)	295 bp
Tssr117356	Chr12:101188284-101188319 (-)	374 bp