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Prl2c2 Gene Detail
Summary
  • Symbol
    Prl2c2
  • Name
    prolactin family 2, subfamily c, member 2
  • Synonyms
    MRP-1, Plf, Plf1, PLF-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97618
    NCBI Gene: 18811
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:13170710-13179968 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 5.18 cM
  • Mapping Data
    12 experiments
Strain
Comparison
more
  • SNPs within 2kb
    18 from dbSNP Build 142
  • Strain Annotations
    7
  • RFLP
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97618
 protein coding gene Chr13:13170705-13179978 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0020361
 protein coding gene Chr13:24953430-24976062 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0020177
 protein coding gene Chr13:9780255-9795785 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0018382
 protein coding gene Chr13:23503754-23509974 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0020114
 protein coding gene Chr13:27540291-27556546 (+)
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019251
 protein coding gene Chr13:24028323-24041198 (+)
WSB/EiJ MGP_WSBEiJ_G0019575
 protein coding gene Chr13:9930505-9940626 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from multigenic genotypes
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    838
  • Tissues
    36
  • cDNA Data
    53
  • Literature Summary
    71
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079092 Ensembl Gene Model | MGI Sequence Detail 9259 C57BL/6J ±  kb
transcript ENSMUST00000110594 Ensembl | MGI Sequence Detail 842 Not Applicable  
polypeptide ENSMUSP00000106224 Ensembl | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    Genomic 3
    cDNA 55
    Primer pair 4
    Other 8

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-13358
References
more
  • Summaries
    All 115
    Developmental Gene Expression 71
    Gene Ontology 8
    Phenotypes 3
  • Earliest
    J:30957 Linzer DI, et al., Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family. Proc Natl Acad Sci U S A. 1984 Jul;81(14):4255-9
  • Latest
    J:345473 Lee JG, et al., PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development. Nat Commun. 2024 Feb 19;15(1):1487
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory