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Prl7d1 Gene Detail
Summary
  • Symbol
    Prl7d1
  • Name
    prolactin family 7, subfamily d, member 1
  • Synonyms
    Plfr, PLF-RP, PRP
  • Feature Type
    protein coding gene
  • IDs
    MGI:97619
    NCBI Gene: 18814
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27892981-27900720 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.60 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    299 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97619
 protein coding gene Chr13:27890320-27900720 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020405
 protein coding gene Chr13:25342403-25350428 (-)
A/J MGP_AJ_G0020356
 protein coding gene Chr13:24790887-24798598 (-)
AKR/J MGP_AKRJ_G0020336
 protein coding gene Chr13:25140810-25148519 (-)
BALB/cJ MGP_BALBcJ_G0020354
 protein coding gene Chr13:24813958-24822780 (-)
C3H/HeJ MGP_C3HHeJ_G0020157
 protein coding gene Chr13:25250039-25296774 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020791
 protein coding gene Chr13:26237322-26266333 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018376
 protein coding gene Chr13:23360392-23367883 (-)
CAST/EiJ MGP_CASTEiJ_G0019675
 protein coding gene Chr13:24925025-24933563 (-)
CBA/J MGP_CBAJ_G0020111
 protein coding gene Chr13:27348131-27357372 (-)
DBA/2J MGP_DBA2J_G0020235
 protein coding gene Chr13:24330658-24338309 (-)
FVB/NJ MGP_FVBNJ_G0020221
 protein coding gene Chr13:23937562-23947654 (-)
LP/J MGP_LPJ_G0020311
 protein coding gene Chr13:25604232-25613043 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020248
 protein coding gene Chr13:27699752-27708309 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020831
 protein coding gene Chr13:24999127-25021058 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0019245
 protein coding gene Chr13:23887568-23895260 (-)
WSB/EiJ MGP_WSBEiJ_G0019735
 protein coding gene Chr13:25171278-25179509 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female mice homozygous for a null allele display reduced litter sizes and placental abnormalities that vary with the sex of the fetus.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    744
  • Tissues
    15
  • cDNA Data
    35
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 18814 NCBI Gene Model | MGI Sequence Detail 7740 C57BL/6J ±  kb
    transcript NM_011120 RefSeq | MGI Sequence Detail 997 C57BL/6  
    polypeptide P04769 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 38
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13359
    References
    more
    • Summaries
      All 50
      Developmental Gene Expression 12
      Gene Ontology 6
      Phenotypes 13
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory