Prt1 Gene Detail

Summary

• Symbol
  Prt1
• Name
  pancreatic proteinase 1
• Synonyms
  Prt-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97777
  NCBI Gene: 104299
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

Prt1 controls electrophoretic patterns and activity level of trypsin I. The a allele determines two bands in CBA/J, DBA/2 and C57BL/6; the b allele determines one anodal band in C57L, DDK, NC and MOL-A. Prt1 has a parallel effect on the electrophoretic properties of trypsinogen.

Sequences &
Gene Models

• NCBI Gene
  104299

Other
Accession IDs

MGD-MRK-13633, MGD-MRK-13639

References

• Summaries
  All 6
• Earliest
  J:5539 Watanabe T, et al., Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus). Biochem Genet. 1974 Nov;12(5):419-28
• Latest
  J:9741 Watanabe T, et al., Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus. Biochem Genet. 1989 Feb;27(1-2):119-30