Rpl37a MGI Mouse Gene Detail - MGI:98068

Symbol

Rpl37a
Name

ribosomal protein L37a

Feature Type

protein coding gene
IDs

MGI:98068
NCBI Gene: 19981
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr1:72750449-72752972 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 36.87 cM
Mapping Data

1 experiment

SNPs within 2kb

258 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98068	protein coding gene	Chr1:72750426-72752972 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016135	protein coding gene	Chr1:73240241-73242790 (+)
A/J	MGP_AJ_G0016118	protein coding gene	Chr1:70658536-70661086 (+)
AKR/J	MGP_AKRJ_G0016075	protein coding gene	Chr1:72640686-72643236 (+)
BALB/cJ	MGP_BALBcJ_G0016073	protein coding gene	Chr1:70740193-70743507 (+)
C3H/HeJ	MGP_C3HHeJ_G0015904	protein coding gene	Chr1:72956310-72958860 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016526	protein coding gene	Chr1:76073205-76075754 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014247	protein coding gene	Chr1:66318235-66320665 (+)
CAST/EiJ	MGP_CASTEiJ_G0015488	protein coding gene	Chr1:72251771-72254313 (+)
CBA/J	MGP_CBAJ_G0015877	protein coding gene	Chr1:78560475-78563886 (+)
DBA/2J	MGP_DBA2J_G0015978	protein coding gene	Chr1:70007055-70009605 (+)
FVB/NJ	MGP_FVBNJ_G0015981	protein coding gene	Chr1:69194315-69196864 (+)
LP/J	MGP_LPJ_G0016050	protein coding gene	Chr1:74291744-74294323 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016001	protein coding gene	Chr1:82016370-82018917 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016573	protein coding gene	Chr1:72677495-72680044 (+)
PWK/PhJ	MGP_PWKPhJ_G0015275	protein coding gene	Chr1:69461175-69464499 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015053	protein coding gene	Chr1:72030599-72032895 (+)
WSB/EiJ	MGP_WSBEiJ_G0015550	protein coding gene	Chr1:72498831-72501380 (+)

Human Ortholog

RPL37A, ribosomal protein L37a

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL37A, ribosomal protein L37a
Synonyms

eL43, L37A
Links

HGNC:10348

NCBI Gene ID: 6168

neXtProt AC: NX_P61513

UniProt: P61513
Chr Location

2q35; chr2:216498825-216579180 (+) GRCh38

MGI Vertebrate Homology

Rpl37a stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: RPL37A
Gene Tree

Rpl37a

less

Phenotype Summary

10 phenotype references

All Mutations and Alleles

6
Chemically induced (other)

1
Gene trapped

2
Radiation induced

1
Targeted

2
Genomic Mutations

2 involving Rpl37a
Find Mice (IMSR)

4 strains or lines available

less

All GO Annotations

17
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

716
Tissues

6
cDNA Data

18
Literature Summary

6

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl37a

less

All Sequences

57
RefSeq

2
UniProt

7
CCDS

CCDS35610.1

Ensembl

ENSMUSG00000046330 (Evidence)
NCBI Gene

19981

			Length	Strain/Species	Flank
genomic	ENSMUSG00000046330	Ensembl Gene Model \| MGI Sequence Detail	2524	C57BL/6J	± kb
transcript	ENSMUST00000059980	Ensembl \| MGI Sequence Detail	558	Not Applicable
polypeptide	ENSMUSP00000058919	Ensembl \| MGI Sequence Detail	92	Not Applicable

less

UniProt

7 Sequences
Protein Ontology

PR:000014223 large ribosomal subunit protein eL43

(term hierarchy)
PDB

6SWA, 7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR011331 Large ribosomal subunit protein eL37/eL43

IPR002674 Large ribosomal subunit protein eL43

IPR011332 Zinc-binding ribosomal protein
GlyGen

P61514 1 site, 1 O-linked glycan (1 site)

less

All nucleic 21

cDNA 19

Primer pair 2

Microarray probesets 8

less

MGD-MRK-14091

Summaries

All 40

Developmental Gene Expression 6

Gene Ontology 6

Phenotypes 10
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731

TSS for Rpl37a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr7309	Chr1:72750397-72750411 (+)	-45 bp
Tssr7310	Chr1:72750418-72750455 (+)	-12 bp
Tssr7311	Chr1:72750480-72750489 (+)	36 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24