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Rv2 QTL Detail
Summary
  • Symbol
    Rv2
  • Name
    Rauscher leukemia virus susceptibility 2
  • Synonyms
    Rv-2
  • Feature Type
    QTL
  • IDs
    MGI:98210
    NCBI Gene: 107725
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 9, cM position of peak correlated region/marker: Syntenic
  • Mapping Data
    1 experiment
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This locus affects susceptibility to the spleen focus-forming component of Rauscher leukemia virus. The dominant resistance allele is found in C57BL/6 and C57BL/10 strains; the recessive susceptibility allele in BALB/c and CBA/Lac. Rv2 may be identical to Mst1r.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-14256, MGD-MRK-14259
References
more
  • Summaries
    All 4
    Phenotypes 1
  • Earliest
    J:5425 Toth FD, et al., Inheritance of susceptibility and resistance to Rauscher leukaemia virus. Acta Microbiol Acad Sci Hung. 1973;20(3):183-9
  • Latest
    J:7613 Heller E, et al., Chromosomal assignment of two murine genes controlling susceptibility to spleen focus formation by Rauscher leukemia virus. Exp Hematol. 1984 Sep;12(8):645-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory