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Sar1a Gene Detail
Summary
  • Symbol
    Sar1a
  • Name
    secretion associated Ras related GTPase 1A
  • Synonyms
    1600019H17Rik, Sara1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98230
    NCBI Gene: 20224
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:61516096-61529076 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 32.26 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    331 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98230
 protein coding gene Chr10:61516078-61529076 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017285
 protein coding gene Chr10:61041961-61054720 (+)
A/J MGP_AJ_G0017263
 protein coding gene Chr10:59208732-59221717 (+)
AKR/J MGP_AKRJ_G0017223
 protein coding gene Chr10:60753789-60766774 (+)
BALB/cJ MGP_BALBcJ_G0017223
 protein coding gene Chr10:59284503-59297488 (+)
C3H/HeJ MGP_C3HHeJ_G0017046
 protein coding gene Chr10:60656350-60669335 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017681
 protein coding gene Chr10:63227561-63240546 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015372
 protein coding gene Chr10:56185829-56199175 (+)
CAST/EiJ MGP_CASTEiJ_G0016617
 protein coding gene Chr10:60673740-60688401 (+)
CBA/J MGP_CBAJ_G0017018
 protein coding gene Chr10:65590784-65603767 (+)
DBA/2J MGP_DBA2J_G0017123
 protein coding gene Chr10:58479980-58492965 (+)
FVB/NJ MGP_FVBNJ_G0017117
 protein coding gene Chr10:57731678-57744628 (+)
LP/J MGP_LPJ_G0017198
 protein coding gene Chr10:61440340-61453518 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017145
 protein coding gene Chr10:67887574-67900559 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017719
 protein coding gene Chr10:60579544-60592722 (+)
PWK/PhJ MGP_PWKPhJ_G0016400
 protein coding gene Chr10:58326861-58340167 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016183
 protein coding gene Chr10:59935263-59950187 (+)
WSB/EiJ MGP_WSBEiJ_G0016681
 protein coding gene Chr10:60494490-60507480 (+)



Homology
more
  • Human Ortholog
    SAR1A, secretion associated Ras related GTPase 1A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SAR1A, secretion associated Ras related GTPase 1A
  • Synonyms
    masra2, SAR1, Sara, SARA1
  • Links
    NCBI Gene ID: 56681
    neXtProt AC: NX_Q9NR31
    UniProt: Q9NR31

  • Chr Location
    10q22.1; chr10:70147289-70170523 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1036
  • Tissues
    24
  • cDNA Data
    18
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20224 NCBI Gene Model | MGI Sequence Detail 12981 C57BL/6J ±  kb
transcript NM_001406330 RefSeq | MGI Sequence Detail 2877 C57BL/6  
polypeptide P36536 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-14289, MGI:1915163
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:349757 Tang VT, et al., Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2322164121
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory