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Ccl6 Gene Detail
Summary
  • Symbol
    Ccl6
  • Name
    C-C motif chemokine ligand 6
  • Synonyms
    c10, MRP-1, Scya6
  • Feature Type
    protein coding gene
  • IDs
    MGI:98263
    NCBI Gene: 20305
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:83478712-83483913 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 50.85 cM
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    277 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98263
protein coding gene Chr11:83478708-83483913 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018854
protein coding gene Chr11:84933109-84938344 (-)
A/J MGP_AJ_G0018821
protein coding gene Chr11:81699909-81705229 (-)
AKR/J MGP_AKRJ_G0018791
protein coding gene Chr11:84136879-84142080 (-)
BALB/cJ MGP_BALBcJ_G0018794
protein coding gene Chr11:82116380-82121587 (-)
C3H/HeJ MGP_C3HHeJ_G0018608
protein coding gene Chr11:84193333-84198568 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019246
protein coding gene Chr11:87533203-87538392 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016880
protein coding gene Chr11:78819175-78825280 (-)
CAST/EiJ MGP_CASTEiJ_G0018163
protein coding gene Chr11:84772187-84777530 (-)
CBA/J MGP_CBAJ_G0018579
protein coding gene Chr11:91289432-91294667 (-)
DBA/2J MGP_DBA2J_G0018687
protein coding gene Chr11:81298691-81304022 (-)
FVB/NJ MGP_FVBNJ_G0018676
protein coding gene Chr11:80782254-80787449 (-)
LP/J MGP_LPJ_G0018757
protein coding gene Chr11:85480463-85485690 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018703
protein coding gene Chr11:91468590-91473803 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019286
protein coding gene Chr11:84409742-84414954 (-)
PWK/PhJ MGP_PWKPhJ_G0017932
protein coding gene Chr11:82056599-82061860 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017724
protein coding gene Chr11:83943913-83947919 (-)
WSB/EiJ MGP_WSBEiJ_G0018214
protein coding gene Chr11:84267243-84272478 (-)



Homology
more
  • Human Ortholog
    CCL15, C-C motif chemokine ligand 15
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL15, C-C motif chemokine ligand 15
  • Synonyms
    HCC-2, HMRP-2B, LKN-1, LKN1, MIP-1D, MIP-1 delta, MIP-5, MRP-2B, NCC-3, NCC3, SCYA15, SCYL3, SY15
  • Links
    NCBI Gene ID: 6359
    neXtProt AC: NX_Q16663
    UniProt: Q16663

  • Chr Location
    17q12; chr17:35996440-36001553 (-)  GRCh38

  • Human Ortholog
    CCL23, C-C motif chemokine ligand 23
  • Synonyms
    Ckb-8, CKb8, Ckb-8-1, CK-BETA-8, hmrp-2a, MIP-3, MIP3, MPIF-1, SCYA23
  • Links
    NCBI Gene ID: 6368
    neXtProt AC: NX_P55773
    UniProt: P55773

  • Chr Location
    17q12; chr17:36013056-36017972 (-)  GRCh38

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    20 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    4
  • Transgenic
    4
  • Genomic Mutations
    3 involving Ccl6
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20305 NCBI Gene Model | MGI Sequence Detail 5202 C57BL/6J ±  kb
transcript NM_009139 RefSeq | MGI Sequence Detail 1436 ZRU/MplStud  
polypeptide P27784 UniProt | EBI | MGI Sequence Detail 116 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 58
    Genomic 6
    cDNA 50
    Primer pair 1
    Other 1

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-14337
References
more
  • Summaries
    All 66
    Developmental Gene Expression 6
    Diseases 1
    Gene Ontology 6
    Phenotypes 20
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:358278 Yang Y, et al., Erythrocytic alpha-Synuclein and the Gut Microbiome: Kindling of the Gut-Brain Axis in Parkinson's Disease. Mov Disord. 2024 Jan;39(1):40-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory