Snrpd2 MGI Mouse Gene Detail - MGI:98345 - small nuclear ribonucleoprotein D2

Symbol

Snrpd2
Name

small nuclear ribonucleoprotein D2
Synonyms

1810009A06Rik, SMD2

Feature Type

protein coding gene
IDs

MGI:98345
NCBI Gene: 107686
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr7:18883370-18886659 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 9.46 cM
Mapping Data

1 experiment

SNPs within 2kb

194 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98345	protein coding gene	Chr7:18883370-18887467 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031762	protein coding gene	Chr7:17111029-17116946 (+)
A/J	MGP_AJ_G0031738	protein coding gene	Chr7:16791637-16795456 (+)
AKR/J	MGP_AKRJ_G0031664	protein coding gene	Chr7:17248623-17252442 (+)
BALB/cJ	MGP_BALBcJ_G0031743	protein coding gene	Chr7:16983691-16987510 (+)
C3H/HeJ	MGP_C3HHeJ_G0031465	protein coding gene	Chr7:17512837-17517423 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032209	protein coding gene	Chr7:17998573-18002393 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029275	protein coding gene	Chr7:18436916-18440772 (+)
CAST/EiJ	MGP_CASTEiJ_G0030808	protein coding gene	Chr7:13910159-13914368 (+)
CBA/J	MGP_CBAJ_G0031427	protein coding gene	Chr7:18652313-18658537 (+)
DBA/2J	MGP_DBA2J_G0031582	protein coding gene	Chr7:16726647-16730466 (+)
FVB/NJ	MGP_FVBNJ_G0031534	protein coding gene	Chr7:16590569-16594388 (+)
LP/J	MGP_LPJ_G0031665	protein coding gene	Chr7:17451958-17455767 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031570	protein coding gene	Chr7:18508447-18513612 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032237	protein coding gene	Chr7:16858591-16862410 (+)
PWK/PhJ	MGP_PWKPhJ_G0030532	protein coding gene	Chr7:13815309-13819487 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030359	protein coding gene	Chr7:11545463-11556572 (+)
WSB/EiJ	MGP_WSBEiJ_G0030908	protein coding gene	Chr7:17065114-17068933 (+)

Human Ortholog

SNRPD2, small nuclear ribonucleoprotein D2 polypeptide

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SNRPD2, small nuclear ribonucleoprotein D2 polypeptide
Synonyms

Sm-D2, SMD2, SNRPD1
Links

HGNC:11159

NCBI Gene ID: 6633

neXtProt AC: NX_P62316

UniProt: P62316
Chr Location

19q13.32; chr19:45687454-45692569 (-) GRCh38

MGI Vertebrate Homology

Snrpd2 stringent orthology
1 human;1 mouse;2 rat;1 zebrafish
HCOP

vertebrate homology predictions: SNRPD2
Gene Tree

Snrpd2

Diseases

1 with human SNRPD2 associations

				Human Disease	Mouse Models
				systemic lupus erythematosus IDs systemic lupus erythematosus DOID:9074 ICD10CM:M32.9 ICD9CM:710.0 KEGG:05322 MESH:D008180 NCI:C3201 OMIM:152700 OMIM:300809 OMIM:605480 OMIM:608437 OMIM:609903 OMIM:609939 OMIM:610065 OMIM:610066 OMIM:612254 OMIM:612378 OMIM:613145 OMIM:614420 ORDO:536 UMLS_CUI:C0024141

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

10
Endonuclease-mediated

1
Gene trapped

7
Targeted

2
Find Mice (IMSR)

11 strains or lines available

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All GO Annotations

40
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

707
Tissues

1
cDNA Data

186
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase snrpd2

ZFIN snrpd2

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All Sequences

40
RefSeq

4
UniProt

2
CCDS

CCDS20892.1

Ensembl

ENSMUSG00000040824 (Evidence)
NCBI Gene

107686

			Length	Strain/Species	Flank
genomic	107686	NCBI Gene Model \| MGI Sequence Detail	3290	C57BL/6J	± kb
transcript	NM_026943	RefSeq \| MGI Sequence Detail	511	C57BL/6
polypeptide	P62317	UniProt \| EBI \| MGI Sequence Detail	118	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000015344 small nuclear ribonucleoprotein Sm D2

(term hierarchy)
InterPro Domains

IPR010920 LSM domain superfamily

IPR027248 Small nuclear ribonucleoprotein Sm D2

IPR047575 Sm domain

IPR001163 Sm domain, eukaryotic/archaea-type

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All nucleic 187

cDNA 187

Microarray probesets 6

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MGD-MRK-14475, MGI:1916357

Summaries

All 35

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 8
Earliest

J:1159 Mitsuda T, et al., The murine Sm-D autoantigen: multiple genes, genetic polymorphism, evolutionary conservation and lack of intervening sequences in the coding region. J Autoimmun. 1992 Jun;5(3):277-87
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Snrpd2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr64789	Chr7:18883735-18883769 (+)	382 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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