Sto1 Gene Detail

Summary

• Symbol
  Sto1
• Name
  16 steroid alpha-hydroxylase 1
• Synonyms
  Sto-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98435
  NCBI Gene: 107511
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

This locus controls activity in liver of females of a 16alpha-hydroxylase with high affinity for testosterone and progesterone and low affinity for pregnenolone. 129/J carries the low activity allele; C57BL/6, DBA/2, AKR, C3H/I and BALB/c the high activity allele. Heterozygotes are intermediate.

Sequences &
Gene Models

• NCBI Gene
  107511

Other
Accession IDs

MGD-MRK-14629, MGD-MRK-14631

References

• Summaries
  All 3
• Earliest
  J:7585 Pasleau F, et al., Genetic regulation of hepatic steroid 16 alpha-hydroxylase activities in inbred strains of mice. Endocrinology. 1984 Oct;115(4):1371-9