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Tst Gene Detail
Summary
  • Symbol
    Tst
  • Name
    thiosulfate sulfurtransferase, mitochondrial
  • Synonyms
    Rhodanese
  • Feature Type
    protein coding gene
  • IDs
    MGI:98852
    NCBI Gene: 22117
  • Alliance
  • Transcription Start Sites
    4 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr15:78283756-78290065 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 37.47 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98852
protein coding gene Chr15:78283756-78290107 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022041
protein coding gene Chr15:78593545-78599828 (-)
A/J MGP_AJ_G0022002
protein coding gene Chr15:75897908-75904205 (-)
AKR/J MGP_AKRJ_G0021977
protein coding gene Chr15:77986525-77992810 (-)
BALB/cJ MGP_BALBcJ_G0022008
protein coding gene Chr15:75871285-75877564 (-)
C3H/HeJ MGP_C3HHeJ_G0021779
protein coding gene Chr15:78004130-78010427 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022451
protein coding gene Chr15:81695505-81702859 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019981
protein coding gene Chr15:72395845-72402168 (-)
CAST/EiJ MGP_CASTEiJ_G0021300
protein coding gene Chr15:78679165-78687589 (-)
CBA/J MGP_CBAJ_G0021744
protein coding gene Chr15:84216956-84223245 (-)
DBA/2J MGP_DBA2J_G0021873
protein coding gene Chr15:75381252-75387537 (-)
FVB/NJ MGP_FVBNJ_G0021851
protein coding gene Chr15:74381803-74388100 (-)
LP/J MGP_LPJ_G0021941
protein coding gene Chr15:78799285-78805566 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021871
protein coding gene Chr15:89411977-89418260 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022465
protein coding gene Chr15:78029141-78035468 (-)
PWK/PhJ MGP_PWKPhJ_G0021042
protein coding gene Chr15:75379756-75386074 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020879
protein coding gene Chr15:77799371-77807629 (-)
WSB/EiJ MGP_WSBEiJ_G0021352
protein coding gene Chr15:78381748-78388030 (-)



Homology
more
  • Human Ortholog
    TST, thiosulfate sulfurtransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TST, thiosulfate sulfurtransferase
  • Synonyms
    RDS
  • Links
    NCBI Gene ID: 7263
    neXtProt AC: NX_Q16762
    UniProt: Q16762

  • Chr Location
    22q12.3; chr22:37010859-37020183 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    33 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22117 NCBI Gene Model | MGI Sequence Detail 6310 C57BL/6J ±  kb
    transcript NM_009437 RefSeq | MGI Sequence Detail 1102 ZRU/MplStud  
    polypeptide P52196 UniProt | EBI | MGI Sequence Detail 297 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 144
      cDNA 143
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-15279
    References
    more
    • Summaries
      All 76
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 10
      Phenotypes 33
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory