vc Gene Detail

Summary

• Symbol
  vc
• Name
  vacillans

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98925
  NCBI Gene: 22328
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr4:57190841-59041899 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, Syntenic
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

Homozygous mutants exhibit tremors and swaying gait, increased peri-weaning mortality, reduced growth, aggressiveness, and muscle strength, partial hearing loss, markedly delayed male sexual maturation, and impaired maternal ability.

Sequences &
Gene Models

• NCBI Gene
  22328

Other
Accession IDs

MGD-MRK-15383

References

• Summaries
  All 5

  Phenotypes 3
• Earliest
  J:297 Sirlin JL, Vacillans, a neurological mutant in the house mouse linked with brown. J Genet. 1956;54(1):42-8
• Latest
  J:72647 Cuajungco MP, et al., Cloning, characterization, and genomic structure of the mouse Ikbkap gene. DNA Cell Biol. 2001 Sep;20(9):579-86