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Zfp53 Gene Detail
Summary
  • Symbol
    Zfp53
  • Name
    zinc finger protein 53
  • Synonyms
    D030067O06Rik, KRAZ1, zfas8, Zfp118, Zfp-53
  • Feature Type
    protein coding gene
  • IDs
    MGI:99200
    NCBI Gene: 24132
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:21709260-21730735 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 11.40 cM, cytoband A3.2
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    634 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99200
 protein coding gene Chr17:21709179-21742899 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023230
 protein coding gene Chr17:20228294-20247409 (+)
A/J MGP_AJ_G0023197
 protein coding gene Chr17:19486568-19505010 (+)
AKR/J MGP_AKRJ_G0023166
 protein coding gene Chr17:19512547-19533149 (+)
BALB/cJ MGP_BALBcJ_G0023195
 protein coding gene Chr17:19664715-19688454 (+)
C3H/HeJ MGP_C3HHeJ_G0022956
 protein coding gene Chr17:19895132-19915636 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023638
 protein coding gene Chr17:20899521-20920259 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021130
 protein coding gene Chr17:17013993-17033208 (+)
CAST/EiJ MGP_CASTEiJ_G0022469
 protein coding gene Chr17:19608765-19630882 (+)
CBA/J MGP_CBAJ_G0022931
 protein coding gene Chr17:21600583-21624671 (+)
DBA/2J MGP_DBA2J_G0023065
 protein coding gene Chr17:19114908-19135674 (+)
FVB/NJ MGP_FVBNJ_G0023031
 protein coding gene Chr17:18901629-18922302 (+)
LP/J MGP_LPJ_G0023142
 protein coding gene Chr17:20225713-20245411 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023051
 protein coding gene Chr17:21496923-21537571 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023678
 protein coding gene Chr17:19879745-19898531 (+)
PWK/PhJ MGP_PWKPhJ_G0022216
 protein coding gene Chr17:18003695-18022843 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022036
 protein coding gene Chr17:17961944-17986391 (+)
WSB/EiJ MGP_WSBEiJ_G0022529
 protein coding gene Chr17:19974698-20006405 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
Homozygous disruption of this locus results in pigmentation abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    767
  • Tissues
    40
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057409 Ensembl Gene Model | MGI Sequence Detail 21476 C57BL/6J ±  kb
transcript ENSMUST00000076664 Ensembl | MGI Sequence Detail 2058 Not Applicable  
polypeptide ENSMUSP00000075960 Ensembl | MGI Sequence Detail 652 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 3
    cDNA 13
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15897, MGD-MRK-15952, MGI:1344343, MGI:2443960
References
more
  • Summaries
    All 46
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 22
  • Earliest
    J:84774 Dunn LC, Studies of the genetic variability in populations of wild house mice. II. Analysis of eight additional alleles at locus T. Genetics. 1957;42:299-311
  • Latest
    J:273736 Charron Y, et al., Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. PLoS Genet. 2019 Feb;15(2):e1007964
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory