About   Help   FAQ
Arl1 Gene Detail
Summary
  • Symbol
    Arl1
  • Name
    ADP-ribosylation factor-like 1
  • Synonyms
    2310008D22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:99436
    NCBI Gene: 104303
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:88566720-88579956 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 44.19 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    350 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99436
 protein coding gene Chr10:88566720-88579956 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017631
 protein coding gene Chr10:89855925-89868426 (+)
A/J MGP_AJ_G0017610
 protein coding gene Chr10:86802167-86814848 (+)
AKR/J MGP_AKRJ_G0017568
 protein coding gene Chr10:89277888-89292004 (+)
BALB/cJ MGP_BALBcJ_G0017573
 protein coding gene Chr10:87076561-87089652 (+)
C3H/HeJ MGP_C3HHeJ_G0017396
 protein coding gene Chr10:89266491-89280924 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018030
 protein coding gene Chr10:92856558-92871388 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015712
 protein coding gene Chr10:82555596-82568703 (+)
CAST/EiJ MGP_CASTEiJ_G0016961
 protein coding gene Chr10:89180349-89196941 (+)
CBA/J MGP_CBAJ_G0017365
 protein coding gene Chr10:96709569-96727390 (+)
DBA/2J MGP_DBA2J_G0017471
 protein coding gene Chr10:85944489-85958655 (+)
FVB/NJ MGP_FVBNJ_G0017463
 protein coding gene Chr10:85148424-85159634 (+)
LP/J MGP_LPJ_G0017545
 protein coding gene Chr10:90523955-90536013 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017494
 protein coding gene Chr10:98198351-98214363 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018067
 protein coding gene Chr10:89115168-89129551 (+)
PWK/PhJ MGP_PWKPhJ_G0016742
 protein coding gene Chr10:85941559-85955939 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016530
 protein coding gene Chr10:87864100-87877831 (+)
WSB/EiJ MGP_WSBEiJ_G0017020
 protein coding gene Chr10:89109720-89124894 (+)



Homology
more
  • Human Ortholog
    ARL1, ARF like GTPase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL1, ARF like GTPase 1
  • Synonyms
    ARFL1
  • Links
    NCBI Gene ID: 400
    neXtProt AC: NX_P40616
    UniProt: P40616

  • Chr Location
    12q23.2; chr12:101393116-101407820 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Targeted
    5
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Arl1
  • Find Mice (IMSR)
    12 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    745
  • Tissues
    30
  • cDNA Data
    207
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 104303 NCBI Gene Model | MGI Sequence Detail 13237 C57BL/6J ±  kb
transcript NM_025859 RefSeq | MGI Sequence Detail 842 C57BL/6  
polypeptide P61211 UniProt | EBI | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000004273 ADP-ribosylation factor-like protein 1
    (term hierarchy)
  • InterPro Domains
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR006689 Small GTPase superfamily, ARF/SAR type
    IPR024156 Small GTPase superfamily, ARF type
    IPR005225 Small GTP-binding protein domain
  • GlyGen
    P61211 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 209
    cDNA 208
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-16200, MGI:1914191, MGI:2143203
References
more
  • Summaries
    All 49
    Developmental Gene Expression 5
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:266268 Kowalchuk AM, et al., Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis. Dev Biol. 2018 Oct 15;442(2):220-235
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory