About   Help   FAQ
Acsm3 Gene Detail
Summary
  • Symbol
    Acsm3
  • Name
    acyl-CoA synthetase medium-chain family member 3
  • Synonyms
    Sa, Sah
  • Feature Type
    protein coding gene
  • IDs
    MGI:99538
    NCBI Gene: 20216
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:119360106-119384119 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 64.17 cM, cytoband F3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    650 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99538
 protein coding gene Chr7:119360106-119386736 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032917
 protein coding gene Chr7:123691710-123718963 (+)
A/J MGP_AJ_G0032900
 protein coding gene Chr7:120489553-120518231 (+)
AKR/J MGP_AKRJ_G0032832
 protein coding gene Chr7:123600137-123628321 (+)
BALB/cJ MGP_BALBcJ_G0032905
 protein coding gene Chr7:120222163-120248499 (+)
C3H/HeJ MGP_C3HHeJ_G0032615
 protein coding gene Chr7:123500427-123528930 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033411
 protein coding gene Chr7:128584320-128610473 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030383
 protein coding gene Chr7:121927011-121953244 (+)
CAST/EiJ MGP_CASTEiJ_G0031943
 protein coding gene Chr7:115256911-115283079 (+)
CBA/J MGP_CBAJ_G0032588
 protein coding gene Chr7:132882732-132911150 (+)
DBA/2J MGP_DBA2J_G0032740
 protein coding gene Chr7:118541049-118567553 (+)
FVB/NJ MGP_FVBNJ_G0032693
 protein coding gene Chr7:118378378-118404627 (+)
LP/J MGP_LPJ_G0032834
 protein coding gene Chr7:125143773-125172418 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032725
 protein coding gene Chr7:134339234-134373987 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033431
 protein coding gene Chr7:122574686-122602128 (+)
PWK/PhJ MGP_PWKPhJ_G0031651
 protein coding gene Chr7:111453472-111482676 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031497
 protein coding gene Chr7:109328945-109358800 (+)
WSB/EiJ MGP_WSBEiJ_G0032056
 protein coding gene Chr7:123482998-123509837 (+)



Homology
more
  • Human Ortholog
    ACSM3, acyl-CoA synthetase medium chain family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACSM3, acyl-CoA synthetase medium chain family member 3
  • Synonyms
    SA, SAH
  • Links
    NCBI Gene ID: 6296
    neXtProt AC: NX_Q53FZ2
    UniProt: Q53FZ2

  • Chr Location
    16p12.3; chr16:20610243-20797581 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ACSM3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Homozygous null mice are viable and fertile with normal kidney function and morphology and blood pressure similar to wild-type on either a regular or high salt diet.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    820
  • Tissues
    102
  • cDNA Data
    55
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20216 NCBI Gene Model | MGI Sequence Detail 24014 C57BL/6J ±  kb
transcript NM_016870 RefSeq | MGI Sequence Detail 2734 C57BL/6  
polypeptide Q3UNX5 UniProt | EBI | MGI Sequence Detail 580 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 57

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16316
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:35449 Ding YP, et al., Genetic maps of polymorphic DNA loci on rat chromosome 1. Genomics. 1996 Sep 1;36(2):320-7
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory